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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUL1 All Species: 23.94
Human Site: S228 Identified Species: 58.52
UniProt: Q969V5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969V5 NP_078820.2 352 39800 S228 L S S Q D F D S L L Q R Q E S
Chimpanzee Pan troglodytes XP_513168 352 39808 S228 L N S Q D F D S L L Q R Q E S
Rhesus Macaque Macaca mulatta XP_001096167 352 39808 S228 L S S Q D F D S L L Q R Q E S
Dog Lupus familis XP_544520 352 39913 S228 L S S Q D F D S L L Q R Q E S
Cat Felis silvestris
Mouse Mus musculus Q8VCM5 352 39816 S228 L S S Q D F D S L L H R Q E S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515759 358 40283 T234 L S S Q D F D T L L Q R Q E S
Chicken Gallus gallus
Frog Xenopus laevis Q6NTT6 353 40340 G229 L S S M D Y E G L L E K Q E V
Zebra Danio Brachydanio rerio Q5M7X9 341 38566 E222 F L S S A D F E T L L M E Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392813 340 38142 S218 Y L T S M S I S S L L R K L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798763 343 38393 G217 L S L S G Q S G I L R E L R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 94 N.A. 89.7 N.A. N.A. 77.9 N.A. 64.8 44.5 N.A. N.A. 30.6 N.A. 39.2
Protein Similarity: 100 100 100 96.8 N.A. 95.1 N.A. N.A. 89.6 N.A. 82.7 63.9 N.A. N.A. 51.9 N.A. 57.3
P-Site Identity: 100 93.3 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. 53.3 13.3 N.A. N.A. 20 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 100 N.A. 80 26.6 N.A. N.A. 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 70 10 60 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 10 10 0 0 10 10 10 70 10 % E
% Phe: 10 0 0 0 0 60 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 20 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % K
% Leu: 80 20 10 0 0 0 0 0 70 100 20 0 10 10 0 % L
% Met: 0 0 0 10 10 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 60 0 10 0 0 0 0 50 0 70 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 70 0 10 0 % R
% Ser: 0 70 80 30 0 10 10 60 10 0 0 0 0 0 70 % S
% Thr: 0 0 10 0 0 0 0 10 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _