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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUL1 All Species: 26.97
Human Site: Y220 Identified Species: 65.93
UniProt: Q969V5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969V5 NP_078820.2 352 39800 Y220 P K Q G M Q Y Y L S S Q D F D
Chimpanzee Pan troglodytes XP_513168 352 39808 Y220 P K Q G M Q Y Y L N S Q D F D
Rhesus Macaque Macaca mulatta XP_001096167 352 39808 Y220 P K Q G M Q Y Y L S S Q D F D
Dog Lupus familis XP_544520 352 39913 Y220 P K Q G M Q Y Y L S S Q D F D
Cat Felis silvestris
Mouse Mus musculus Q8VCM5 352 39816 Y220 P K Q G M Q Y Y L S S Q D F D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515759 358 40283 Y226 P K Q G L H Y Y L S S Q D F D
Chicken Gallus gallus
Frog Xenopus laevis Q6NTT6 353 40340 Y221 P K D G M L F Y L S S M D Y E
Zebra Danio Brachydanio rerio Q5M7X9 341 38566 Y214 P P T D G S E Y F L S S A D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392813 340 38142 F210 P P L D G T P F Y L T S M S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798763 343 38393 I209 P T S G L D Y I L S L S G Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 94 N.A. 89.7 N.A. N.A. 77.9 N.A. 64.8 44.5 N.A. N.A. 30.6 N.A. 39.2
Protein Similarity: 100 100 100 96.8 N.A. 95.1 N.A. N.A. 89.6 N.A. 82.7 63.9 N.A. N.A. 51.9 N.A. 57.3
P-Site Identity: 100 93.3 100 100 N.A. 100 N.A. N.A. 86.6 N.A. 60 20 N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 80 20 N.A. N.A. 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 20 0 10 0 0 0 0 0 0 70 10 60 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 10 10 0 0 0 0 60 10 % F
% Gly: 0 0 0 80 20 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % I
% Lys: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 20 10 0 0 80 20 10 0 0 0 0 % L
% Met: 0 0 0 0 60 0 0 0 0 0 0 10 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 100 20 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 60 0 0 50 0 0 0 0 0 60 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 10 0 0 0 70 80 30 0 10 10 % S
% Thr: 0 10 10 0 0 10 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 70 80 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _