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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUL1 All Species: 28.48
Human Site: Y263 Identified Species: 69.63
UniProt: Q969V5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969V5 NP_078820.2 352 39800 Y263 F F I L R K Q Y L Q R Q E R L
Chimpanzee Pan troglodytes XP_513168 352 39808 Y263 F F I L R K Q Y L Q R Q E R L
Rhesus Macaque Macaca mulatta XP_001096167 352 39808 Y263 F F I L R K Q Y L Q R Q E R L
Dog Lupus familis XP_544520 352 39913 Y263 F F I L R K H Y L Q R Q E R Q
Cat Felis silvestris
Mouse Mus musculus Q8VCM5 352 39816 Y263 F F I L R K Q Y L H R Q E R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515759 358 40283 Y269 F F L L R R Q Y L R H R E R R
Chicken Gallus gallus
Frog Xenopus laevis Q6NTT6 353 40340 Y264 F F I L R R K Y R H Y K E K Q
Zebra Danio Brachydanio rerio Q5M7X9 341 38566 Y257 L I W T G R R Y Y R Q L K L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392813 340 38142 Y253 G G I V L R R Y W K D R T E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798763 343 38393 F252 C I V L W K W F K R Y Q E Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 94 N.A. 89.7 N.A. N.A. 77.9 N.A. 64.8 44.5 N.A. N.A. 30.6 N.A. 39.2
Protein Similarity: 100 100 100 96.8 N.A. 95.1 N.A. N.A. 89.6 N.A. 82.7 63.9 N.A. N.A. 51.9 N.A. 57.3
P-Site Identity: 100 100 100 86.6 N.A. 93.3 N.A. N.A. 60 N.A. 46.6 6.6 N.A. N.A. 13.3 N.A. 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 N.A. N.A. 86.6 N.A. 73.3 40 N.A. N.A. 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 80 10 0 % E
% Phe: 70 70 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 20 10 0 0 0 0 % H
% Ile: 0 20 70 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 60 10 0 10 10 0 10 10 10 0 % K
% Leu: 10 0 10 80 10 0 0 0 60 0 0 10 0 10 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 50 0 0 40 10 60 0 10 30 % Q
% Arg: 0 0 0 0 70 40 20 0 10 30 50 20 0 60 30 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 10 0 10 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 10 0 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _