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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMEPA1 All Species: 12.12
Human Site: S243 Identified Species: 29.63
UniProt: Q969W9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969W9 NP_064567.2 287 31609 S243 I G H Y P G S S F Q H Q Q S S
Chimpanzee Pan troglodytes XP_512194 276 30878 S236 M G H H P G A S F L H H Q R S
Rhesus Macaque Macaca mulatta XP_001086224 252 27841 Q212 P G S S F Q H Q Q S S G P P S
Dog Lupus familis XP_543070 387 41955 P342 I G H Y P G S P A F Q H Q Q S
Cat Felis silvestris
Mouse Mus musculus Q9D7R2 260 28697 S220 V I G H Y P G S S F Q H Q Q S
Rat Rattus norvegicus NP_001101277 230 25351 S190 I G H Y P G S S F Q Q H Q Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510385 285 31822 A240 I G H Y P G S A F Y Q H Q Q N
Chicken Gallus gallus NP_001026663 286 31938 T240 I G H Y P G A T F Y Q H Q Q N
Frog Xenopus laevis NP_001108307 254 28627 Q214 R S S F Y H C Q Q P N L A T P
Zebra Danio Brachydanio rerio XP_001921199 305 33825 F264 T Y P G S A S F L H Q H S N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.2 87.1 65.3 N.A. 81.8 73.5 N.A. 83.9 83.2 69.6 52.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.7 87.4 68.9 N.A. 86 75.9 N.A. 91.6 91.2 76.6 64.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 13.3 60 N.A. 20 80 N.A. 60 53.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 13.3 60 N.A. 33.3 80 N.A. 73.3 73.3 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 20 10 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 10 0 0 10 50 20 0 0 0 0 0 % F
% Gly: 0 70 10 10 0 60 10 0 0 0 0 10 0 0 0 % G
% His: 0 0 60 20 0 10 10 0 0 10 20 70 0 0 0 % H
% Ile: 50 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 10 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 30 % N
% Pro: 10 0 10 0 60 10 0 10 0 10 0 0 10 10 10 % P
% Gln: 0 0 0 0 0 10 0 20 20 20 60 10 70 50 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 10 20 10 10 0 50 40 10 10 10 0 10 10 60 % S
% Thr: 10 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 50 20 0 0 0 0 20 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _