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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMEPA1
All Species:
16.67
Human Site:
Y219
Identified Species:
40.74
UniProt:
Q969W9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969W9
NP_064567.2
287
31609
Y219
S
G
I
S
A
T
C
Y
G
S
G
G
R
M
E
Chimpanzee
Pan troglodytes
XP_512194
276
30878
C212
S
G
I
S
A
S
T
C
S
S
N
G
R
M
E
Rhesus Macaque
Macaca mulatta
XP_001086224
252
27841
G188
A
T
C
Y
G
S
G
G
R
M
E
G
P
P
P
Dog
Lupus familis
XP_543070
387
41955
Y318
S
G
I
S
A
T
C
Y
G
G
G
G
R
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7R2
260
28697
C196
N
S
G
I
S
A
T
C
Y
S
S
G
G
R
M
Rat
Rattus norvegicus
NP_001101277
230
25351
Y166
S
G
I
S
A
T
C
Y
S
S
G
G
R
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510385
285
31822
Y216
S
G
I
S
A
T
C
Y
G
G
H
G
R
M
E
Chicken
Gallus gallus
NP_001026663
286
31938
Y216
S
G
I
S
A
T
C
Y
G
S
N
G
R
M
E
Frog
Xenopus laevis
NP_001108307
254
28627
R190
T
S
Y
S
S
N
G
R
M
E
G
P
P
P
T
Zebra Danio
Brachydanio rerio
XP_001921199
305
33825
N240
N
S
G
K
S
A
S
N
S
H
V
E
G
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.2
87.1
65.3
N.A.
81.8
73.5
N.A.
83.9
83.2
69.6
52.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.7
87.4
68.9
N.A.
86
75.9
N.A.
91.6
91.2
76.6
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
6.6
93.3
N.A.
13.3
93.3
N.A.
86.6
93.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
20
93.3
N.A.
26.6
93.3
N.A.
86.6
93.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
60
20
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
50
20
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
60
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
60
20
0
10
0
20
10
40
20
40
80
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
60
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
60
10
% M
% Asn:
20
0
0
0
0
10
0
10
0
0
20
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
20
30
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
0
0
60
10
0
% R
% Ser:
60
30
0
70
30
20
10
0
30
50
10
0
0
0
0
% S
% Thr:
10
10
0
0
0
50
20
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
50
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _