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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMBIM1
All Species:
21.82
Human Site:
S281
Identified Species:
53.33
UniProt:
Q969X1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969X1
NP_071435.2
311
34607
S281
G
N
R
K
H
T
I
S
P
E
D
Y
I
T
G
Chimpanzee
Pan troglodytes
XP_001144519
255
28776
E227
R
K
H
T
I
S
P
E
D
Y
I
T
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001089718
311
34619
S281
G
N
R
K
H
T
I
S
P
E
D
Y
I
T
G
Dog
Lupus familis
XP_853016
289
31994
D262
K
H
T
I
S
P
E
D
Y
I
T
G
A
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJZ3
309
34375
S279
G
N
R
K
H
T
I
S
P
E
D
Y
I
T
G
Rat
Rattus norvegicus
O88407
316
35017
S285
G
N
R
R
H
S
L
S
P
E
E
Y
I
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422067
311
34159
S282
G
N
R
K
N
T
L
S
P
E
E
Y
I
Y
G
Frog
Xenopus laevis
Q92125
512
53295
V355
S
I
M
A
R
G
I
V
D
E
S
Q
N
V
N
Zebra Danio
Brachydanio rerio
NP_001005992
324
35869
S293
G
N
R
K
L
S
I
S
P
E
E
Y
V
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A20
256
28150
Y229
K
R
F
T
Y
D
E
Y
I
L
A
S
V
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
99
74.5
N.A.
88
49
N.A.
N.A.
71
22.2
53.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.9
99.6
81
N.A.
93.8
64.2
N.A.
N.A.
82.6
33.5
68.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
66.6
N.A.
N.A.
73.3
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
6.6
N.A.
100
93.3
N.A.
N.A.
93.3
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
10
20
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
20
0
30
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
10
0
70
30
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
60
0
0
0
0
10
0
0
0
0
0
10
10
0
50
% G
% His:
0
10
10
0
40
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
10
0
50
0
10
10
10
0
50
0
0
% I
% Lys:
20
10
0
50
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
20
0
0
10
0
0
0
10
20
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
0
0
10
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
10
10
0
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
10
10
60
10
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
30
0
60
0
0
10
10
0
0
0
% S
% Thr:
0
0
10
20
0
40
0
0
0
0
10
10
0
30
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
20
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
10
10
0
60
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _