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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC1 All Species: 41.82
Human Site: S179 Identified Species: 65.71
UniProt: Q969X5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X5 NP_001026881.1 290 32592 S179 G G A D R L T S N P L A S H D
Chimpanzee Pan troglodytes XP_001145588 424 46112 S313 G G A D R L T S N P L A S H D
Rhesus Macaque Macaca mulatta XP_001099287 379 41317 S268 G G A D R L T S N P L A S H D
Dog Lupus familis XP_852891 290 32583 S179 G G A D R L T S N P L A S H D
Cat Felis silvestris
Mouse Mus musculus Q9DC16 290 32544 S179 G G A D R L T S N P L A S H D
Rat Rattus norvegicus XP_002724642 363 39823 S252 G G A D R L T S N P L A S H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521132 388 43027 S277 G G A D K R S S N P L A S Y D
Chicken Gallus gallus XP_414530 290 32675 S179 E G A D K L S S N P L A S H D
Frog Xenopus laevis Q6NS19 290 32515 S179 G G A D K L A S K A L E S H D
Zebra Danio Brachydanio rerio Q4V8Y6 290 32511 S179 G G A D R L Q S N A L A S H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508375 286 32504 E175 A K R N T S Q E N G L N T H E
Sea Urchin Strong. purpuratus XP_794044 289 32701 S178 E G R D K R D S K S D L S H D
Poplar Tree Populus trichocarpa XP_002322569 351 39853 L239 L D G T A R I L R E T S G I F
Maize Zea mays NP_001150650 387 43848 S275 V E W I Q D N S N G L T G M Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188868 354 40074 L244 L D D T N R I L H D T S G T F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.1 76.2 98.6 N.A. 98.9 78.7 N.A. 71.3 94.4 87.5 89.3 N.A. N.A. N.A. 55.1 61.3
Protein Similarity: 100 68.1 76.5 99.6 N.A. 99.6 79.6 N.A. 73.1 97.5 93.4 95.1 N.A. N.A. N.A. 74.4 75.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 80 66.6 86.6 N.A. N.A. N.A. 20 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 73.3 86.6 N.A. N.A. N.A. 40 46.6
Percent
Protein Identity: 27.9 28.6 N.A. 27.4 N.A. N.A.
Protein Similarity: 41.6 42.8 N.A. 42.3 N.A. N.A.
P-Site Identity: 0 20 N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 67 0 7 0 7 0 0 14 0 60 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 7 74 0 7 7 0 0 7 7 0 0 0 74 % D
% Glu: 14 7 0 0 0 0 0 7 0 7 0 7 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % F
% Gly: 60 74 7 0 0 0 0 0 0 14 0 0 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 74 0 % H
% Ile: 0 0 0 7 0 0 14 0 0 0 0 0 0 7 0 % I
% Lys: 0 7 0 0 27 0 0 0 14 0 0 0 0 0 0 % K
% Leu: 14 0 0 0 0 60 0 14 0 0 80 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 7 7 0 7 0 74 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 54 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 14 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 14 0 47 27 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 7 14 80 0 7 0 14 74 0 0 % S
% Thr: 0 0 0 14 7 0 40 0 0 0 14 7 7 7 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _