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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC1 All Species: 42.12
Human Site: S65 Identified Species: 66.19
UniProt: Q969X5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X5 NP_001026881.1 290 32592 S65 V D D P D K D S G G K I D V S
Chimpanzee Pan troglodytes XP_001145588 424 46112 S199 V D D P D K D S G G K I D V S
Rhesus Macaque Macaca mulatta XP_001099287 379 41317 S154 V D D P D K D S G G K I D V S
Dog Lupus familis XP_852891 290 32583 S65 V D D P D K D S G G K I D V S
Cat Felis silvestris
Mouse Mus musculus Q9DC16 290 32544 S65 V D D P D K D S G G K I D V S
Rat Rattus norvegicus XP_002724642 363 39823 S138 V D D P D K D S G G K I D V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521132 388 43027 S163 V D D P D K D S G G K I D V S
Chicken Gallus gallus XP_414530 290 32675 S65 V D D P D K D S G G K I E V N
Frog Xenopus laevis Q6NS19 290 32515 S65 V D D P D K D S G G K I D V T
Zebra Danio Brachydanio rerio Q4V8Y6 290 32511 S65 V D D P D K D S G G K I D V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508375 286 32504 G64 I D D P G R E G K I D V Q V N
Sea Urchin Strong. purpuratus XP_794044 289 32701 E65 V D N P G E I E R L T V R V N
Poplar Tree Populus trichocarpa XP_002322569 351 39853 I67 V D L Q R G E I L P I H V N I
Maize Zea mays NP_001150650 387 43848 R67 V D T S R G E R L H I N F D V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188868 354 40074 T67 V D L K R G E T L P I H V N M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.1 76.2 98.6 N.A. 98.9 78.7 N.A. 71.3 94.4 87.5 89.3 N.A. N.A. N.A. 55.1 61.3
Protein Similarity: 100 68.1 76.5 99.6 N.A. 99.6 79.6 N.A. 73.1 97.5 93.4 95.1 N.A. N.A. N.A. 74.4 75.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 93.3 100 N.A. N.A. N.A. 26.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. 60 53.3
Percent
Protein Identity: 27.9 28.6 N.A. 27.4 N.A. N.A.
Protein Similarity: 41.6 42.8 N.A. 42.3 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 74 0 67 0 67 0 0 0 7 0 60 7 0 % D
% Glu: 0 0 0 0 0 7 27 7 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 0 0 14 20 0 7 67 67 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 14 0 0 0 % H
% Ile: 7 0 0 0 0 0 7 7 0 7 20 67 0 0 7 % I
% Lys: 0 0 0 7 0 67 0 0 7 0 67 0 0 0 0 % K
% Leu: 0 0 14 0 0 0 0 0 20 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 7 0 14 20 % N
% Pro: 0 0 0 80 0 0 0 0 0 14 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 20 7 0 7 7 0 0 0 7 0 0 % R
% Ser: 0 0 0 7 0 0 0 67 0 0 0 0 0 0 54 % S
% Thr: 0 0 7 0 0 0 0 7 0 0 7 0 0 0 7 % T
% Val: 94 0 0 0 0 0 0 0 0 0 0 14 14 80 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _