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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC1 All Species: 43.33
Human Site: Y196 Identified Species: 68.1
UniProt: Q969X5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X5 NP_001026881.1 290 32592 Y196 L K I V P T V Y E D K S G K Q
Chimpanzee Pan troglodytes XP_001145588 424 46112 Y330 L K I V P T V Y E D K S G K Q
Rhesus Macaque Macaca mulatta XP_001099287 379 41317 Y285 L K I V P T V Y E D K S G K Q
Dog Lupus familis XP_852891 290 32583 Y196 L K I V P T V Y E D K S G K Q
Cat Felis silvestris
Mouse Mus musculus Q9DC16 290 32544 Y196 L K I V P T V Y E D K S G K Q
Rat Rattus norvegicus XP_002724642 363 39823 Y269 L K I V P T V Y E D K S G K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521132 388 43027 Y294 L K I V P T V Y E D K N G K Q
Chicken Gallus gallus XP_414530 290 32675 Y196 L K I V P T V Y E D M S G K Q
Frog Xenopus laevis Q6NS19 290 32515 Y196 L K I V P T V Y E D L N G K Q
Zebra Danio Brachydanio rerio Q4V8Y6 290 32511 Y196 L K I V P T V Y E E L G G K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508375 286 32504 H192 L K I V P S V H E D Y S G T I
Sea Urchin Strong. purpuratus XP_794044 289 32701 Y195 M K I V P T V Y E D L W G T K
Poplar Tree Populus trichocarpa XP_002322569 351 39853 E256 Y I K I V P T E Y R Y I S K D
Maize Zea mays NP_001150650 387 43848 I292 F V K V V P T I Y T D I R G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188868 354 40074 E261 Y I K I V P T E Y R Y L S K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.1 76.2 98.6 N.A. 98.9 78.7 N.A. 71.3 94.4 87.5 89.3 N.A. N.A. N.A. 55.1 61.3
Protein Similarity: 100 68.1 76.5 99.6 N.A. 99.6 79.6 N.A. 73.1 97.5 93.4 95.1 N.A. N.A. N.A. 74.4 75.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 86.6 80 N.A. N.A. N.A. 66.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 86.6 N.A. N.A. N.A. 80 80
Percent
Protein Identity: 27.9 28.6 N.A. 27.4 N.A. N.A.
Protein Similarity: 41.6 42.8 N.A. 42.3 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 74 7 0 0 0 14 % D
% Glu: 0 0 0 0 0 0 0 14 80 7 0 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 7 80 7 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 14 80 14 0 0 0 7 0 0 0 14 0 0 7 % I
% Lys: 0 80 20 0 0 0 0 0 0 0 47 0 0 80 7 % K
% Leu: 74 0 0 0 0 0 0 0 0 0 20 7 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % N
% Pro: 0 0 0 0 80 20 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % Q
% Arg: 0 0 0 0 0 0 0 0 0 14 0 0 7 0 7 % R
% Ser: 0 0 0 0 0 7 0 0 0 0 0 54 14 0 0 % S
% Thr: 0 0 0 0 0 74 20 0 0 7 0 0 0 14 0 % T
% Val: 0 7 0 87 20 0 80 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 14 0 0 0 0 0 0 74 20 0 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _