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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIRH1A All Species: 17.27
Human Site: S272 Identified Species: 34.55
UniProt: Q969X6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X6 NP_116219.2 686 76890 S272 L V P V T S N S S E K Q W V R
Chimpanzee Pan troglodytes XP_511062 775 86288 S363 L V P V T S N S S E K Q W V R
Rhesus Macaque Macaca mulatta XP_001093408 648 72498 G253 S V F D V K S G S A I H K M I
Dog Lupus familis XP_546858 699 78752 S272 L V S V T S N S S E K Q W V R
Cat Felis silvestris
Mouse Mus musculus Q8R2N2 686 76891 S272 L V S M T S N S S E K Q W V R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510337 754 84989 S339 L I S V R S G S S E C Q W I R
Chicken Gallus gallus XP_001232920 364 40029
Frog Xenopus laevis NP_001079449 690 77111 E272 H I A L K A G E S E R Q W V R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648846 696 78649 W282 E E S T S E R W I K F L Q R D
Honey Bee Apis mellifera XP_393722 521 58257 T126 T E D G Y I N T F T V T C D A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784358 747 83111 T303 S G D S V G R T Q F W N G K H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06679 776 87783 N312 F Q F S Q N T N K S Q K N N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 80.4 91.1 N.A. 89.9 N.A. N.A. 60.4 32.6 55 N.A. N.A. 25.2 27.7 N.A. 27
Protein Similarity: 100 88.2 82.2 94.5 N.A. 95.1 N.A. N.A. 75.8 41.8 73.9 N.A. N.A. 47.1 43 N.A. 45.3
P-Site Identity: 100 100 13.3 93.3 N.A. 86.6 N.A. N.A. 60 0 40 N.A. N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 26.6 93.3 N.A. 93.3 N.A. N.A. 73.3 0 66.6 N.A. N.A. 13.3 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 9 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % C
% Asp: 0 0 17 9 0 0 0 0 0 0 0 0 0 9 9 % D
% Glu: 9 17 0 0 0 9 0 9 0 50 0 0 0 0 0 % E
% Phe: 9 0 17 0 0 0 0 0 9 9 9 0 0 0 0 % F
% Gly: 0 9 0 9 0 9 17 9 0 0 0 0 9 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % H
% Ile: 0 17 0 0 0 9 0 0 9 0 9 0 0 9 9 % I
% Lys: 0 0 0 0 9 9 0 0 9 9 34 9 9 9 0 % K
% Leu: 42 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 9 42 9 0 0 0 9 9 9 0 % N
% Pro: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 9 0 0 0 9 0 9 50 9 0 0 % Q
% Arg: 0 0 0 0 9 0 17 0 0 0 9 0 0 9 59 % R
% Ser: 17 0 34 17 9 42 9 42 59 9 0 0 0 0 0 % S
% Thr: 9 0 0 9 34 0 9 17 0 9 0 9 0 0 0 % T
% Val: 0 42 0 34 17 0 0 0 0 0 9 0 0 42 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 9 0 50 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _