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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIRH1A
All Species:
5.76
Human Site:
S426
Identified Species:
11.52
UniProt:
Q969X6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969X6
NP_116219.2
686
76890
S426
N
Y
E
H
D
N
I
S
L
K
R
V
S
K
M
Chimpanzee
Pan troglodytes
XP_511062
775
86288
N515
R
L
N
Y
E
H
D
N
I
S
L
K
R
V
S
Rhesus Macaque
Macaca mulatta
XP_001093408
648
72498
Y400
E
K
V
E
V
K
N
Y
D
A
A
L
R
K
I
Dog
Lupus familis
XP_546858
699
78752
S439
K
M
P
A
F
L
R
S
A
L
Q
I
L
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2N2
686
76891
S426
K
Y
E
R
D
N
I
S
L
Q
R
V
S
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510337
754
84989
H494
Y
G
E
N
N
S
V
H
L
K
R
V
S
K
V
Chicken
Gallus gallus
XP_001232920
364
40029
R115
A
A
N
N
D
G
T
R
L
A
I
G
C
E
D
Frog
Xenopus laevis
NP_001079449
690
77111
V430
E
S
L
S
L
S
R
V
H
K
L
P
Q
L
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648846
696
78649
R438
S
D
P
L
Q
V
E
R
L
V
D
D
L
P
E
Honey Bee
Apis mellifera
XP_393722
521
58257
V273
S
S
G
R
P
Q
W
V
K
G
I
E
R
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784358
747
83111
I483
L
R
A
K
V
P
T
I
P
S
N
L
H
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06679
776
87783
D493
I
V
I
C
S
C
E
D
D
V
F
I
V
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
80.4
91.1
N.A.
89.9
N.A.
N.A.
60.4
32.6
55
N.A.
N.A.
25.2
27.7
N.A.
27
Protein Similarity:
100
88.2
82.2
94.5
N.A.
95.1
N.A.
N.A.
75.8
41.8
73.9
N.A.
N.A.
47.1
43
N.A.
45.3
P-Site Identity:
100
0
6.6
6.6
N.A.
73.3
N.A.
N.A.
46.6
13.3
6.6
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
33.3
20
20
N.A.
86.6
N.A.
N.A.
80
26.6
13.3
N.A.
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
9
0
0
0
0
9
17
9
0
0
0
9
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
25
0
9
9
17
0
9
9
0
9
9
% D
% Glu:
17
0
25
9
9
0
17
0
0
0
0
9
0
9
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
9
9
0
0
9
0
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
9
0
9
0
9
9
0
0
0
9
0
0
% H
% Ile:
9
0
9
0
0
0
17
9
9
0
17
17
0
0
9
% I
% Lys:
17
9
0
9
0
9
0
0
9
25
0
9
0
34
0
% K
% Leu:
9
9
9
9
9
9
0
0
42
9
17
17
17
9
25
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
17
17
9
17
9
9
0
0
9
0
0
0
0
% N
% Pro:
0
0
17
0
9
9
0
0
9
0
0
9
0
17
9
% P
% Gln:
0
0
0
0
9
9
0
0
0
9
9
0
9
0
0
% Q
% Arg:
9
9
0
17
0
0
17
17
0
0
25
0
25
9
0
% R
% Ser:
17
17
0
9
9
17
0
25
0
17
0
0
25
0
17
% S
% Thr:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% T
% Val:
0
9
9
0
17
9
9
17
0
17
0
25
9
9
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
0
9
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _