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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIRH1A
All Species:
26.97
Human Site:
T561
Identified Species:
53.94
UniProt:
Q969X6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969X6
NP_116219.2
686
76890
T561
S
I
P
D
K
Q
Y
T
D
W
S
R
T
V
Q
Chimpanzee
Pan troglodytes
XP_511062
775
86288
T650
S
I
P
D
K
Q
Y
T
D
W
S
R
T
V
Q
Rhesus Macaque
Macaca mulatta
XP_001093408
648
72498
H535
T
V
Q
K
Q
G
F
H
H
L
W
L
Q
R
D
Dog
Lupus familis
XP_546858
699
78752
T574
S
I
P
D
K
Q
Y
T
E
W
S
R
T
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2N2
686
76891
T561
S
I
P
E
K
Q
Y
T
E
W
S
R
S
L
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510337
754
84989
T629
S
I
P
Q
K
Q
Y
T
E
W
S
R
K
I
Q
Chicken
Gallus gallus
XP_001232920
364
40029
D250
L
A
V
S
E
K
E
D
S
I
V
V
G
T
S
Frog
Xenopus laevis
NP_001079449
690
77111
T565
N
I
T
Q
R
Q
Y
T
E
W
G
R
R
V
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648846
696
78649
T573
D
L
V
N
R
I
F
T
C
E
T
N
E
Y
L
Honey Bee
Apis mellifera
XP_393722
521
58257
F408
T
D
S
H
V
R
V
F
N
F
D
V
I
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784358
747
83111
T618
D
I
T
K
H
E
Y
T
P
W
S
R
S
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06679
776
87783
T628
N
L
P
K
E
W
K
T
L
K
E
N
C
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
80.4
91.1
N.A.
89.9
N.A.
N.A.
60.4
32.6
55
N.A.
N.A.
25.2
27.7
N.A.
27
Protein Similarity:
100
88.2
82.2
94.5
N.A.
95.1
N.A.
N.A.
75.8
41.8
73.9
N.A.
N.A.
47.1
43
N.A.
45.3
P-Site Identity:
100
100
0
86.6
N.A.
73.3
N.A.
N.A.
73.3
0
46.6
N.A.
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
86.6
13.3
66.6
N.A.
N.A.
40
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
17
9
0
25
0
0
0
9
17
0
9
0
0
0
9
% D
% Glu:
0
0
0
9
17
9
9
0
34
9
9
0
9
9
0
% E
% Phe:
0
0
0
0
0
0
17
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
9
0
9
0
17
% G
% His:
0
0
0
9
9
0
0
9
9
0
0
0
0
0
9
% H
% Ile:
0
59
0
0
0
9
0
0
0
9
0
0
9
17
0
% I
% Lys:
0
0
0
25
42
9
9
0
0
9
0
0
9
0
0
% K
% Leu:
9
17
0
0
0
0
0
0
9
9
0
9
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
9
0
0
0
0
9
0
0
17
0
0
0
% N
% Pro:
0
0
50
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
17
9
50
0
0
0
0
0
0
9
0
42
% Q
% Arg:
0
0
0
0
17
9
0
0
0
0
0
59
9
9
0
% R
% Ser:
42
0
9
9
0
0
0
0
9
0
50
0
17
0
9
% S
% Thr:
17
0
17
0
0
0
0
75
0
0
9
0
25
9
0
% T
% Val:
0
9
17
0
9
0
9
0
0
0
9
17
0
42
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
59
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
59
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _