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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIRH1A
All Species:
23.64
Human Site:
T581
Identified Species:
47.27
UniProt:
Q969X6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969X6
NP_116219.2
686
76890
T581
H
L
W
L
Q
R
D
T
P
I
T
H
I
S
F
Chimpanzee
Pan troglodytes
XP_511062
775
86288
T670
H
L
W
L
Q
R
D
T
P
I
T
H
I
S
F
Rhesus Macaque
Macaca mulatta
XP_001093408
648
72498
P555
I
S
F
H
P
K
R
P
M
H
I
L
L
H
D
Dog
Lupus familis
XP_546858
699
78752
T594
Y
L
W
L
Q
R
D
T
P
I
T
H
I
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2N2
686
76891
T581
Q
L
W
L
Q
R
D
T
P
I
T
H
I
S
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510337
754
84989
T649
R
L
W
L
E
R
D
T
P
I
I
H
I
A
F
Chicken
Gallus gallus
XP_001232920
364
40029
K270
Q
F
Q
L
L
P
V
K
A
G
G
Q
E
K
R
Frog
Xenopus laevis
NP_001079449
690
77111
T585
R
D
W
L
E
R
D
T
P
I
L
A
I
C
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648846
696
78649
S593
R
H
C
I
N
G
I
S
L
D
P
Q
N
R
N
Honey Bee
Apis mellifera
XP_393722
521
58257
A428
R
N
D
T
D
I
S
A
N
R
I
Q
K
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784358
747
83111
S638
Q
A
W
L
E
K
T
S
V
I
H
Q
M
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06679
776
87783
F648
E
N
S
S
R
L
W
F
W
G
A
T
W
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
80.4
91.1
N.A.
89.9
N.A.
N.A.
60.4
32.6
55
N.A.
N.A.
25.2
27.7
N.A.
27
Protein Similarity:
100
88.2
82.2
94.5
N.A.
95.1
N.A.
N.A.
75.8
41.8
73.9
N.A.
N.A.
47.1
43
N.A.
45.3
P-Site Identity:
100
100
0
93.3
N.A.
93.3
N.A.
N.A.
73.3
6.6
60
N.A.
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
N.A.
N.A.
86.6
6.6
66.6
N.A.
N.A.
13.3
0
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
9
0
9
9
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
9
0
9
0
50
0
0
9
0
0
0
0
9
% D
% Glu:
9
0
0
0
25
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
59
% F
% Gly:
0
0
0
0
0
9
0
0
0
17
9
0
0
0
0
% G
% His:
17
9
0
9
0
0
0
0
0
9
9
42
0
9
0
% H
% Ile:
9
0
0
9
0
9
9
0
0
59
25
0
50
9
0
% I
% Lys:
0
0
0
0
0
17
0
9
0
0
0
0
9
9
0
% K
% Leu:
0
42
0
67
9
9
0
0
9
0
9
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% M
% Asn:
0
17
0
0
9
0
0
0
9
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
9
9
0
9
50
0
9
0
0
0
0
% P
% Gln:
25
0
9
0
34
0
0
0
0
0
0
34
0
0
0
% Q
% Arg:
34
0
0
0
9
50
9
0
0
9
0
0
0
9
9
% R
% Ser:
0
9
9
9
0
0
9
17
0
0
0
0
0
34
9
% S
% Thr:
0
0
0
9
0
0
9
50
0
0
34
9
0
9
0
% T
% Val:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
59
0
0
0
9
0
9
0
0
0
9
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _