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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIRH1A All Species: 4.55
Human Site: Y416 Identified Species: 9.09
UniProt: Q969X6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X6 NP_116219.2 686 76890 Y416 T V S R F F L Y R L N Y E H D
Chimpanzee Pan troglodytes XP_511062 775 86288 F505 Y S T V S R F F L Y R L N Y E
Rhesus Macaque Macaca mulatta XP_001093408 648 72498 P390 D T H L V I R P L M E K V E V
Dog Lupus familis XP_546858 699 78752 R429 H D N I S L Q R V S K M P A F
Cat Felis silvestris
Mouse Mus musculus Q8R2N2 686 76891 Y416 T A S R F F L Y R L K Y E R D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510337 754 84989 L484 A S R L H L H L L K Y G E N N
Chicken Gallus gallus XP_001232920 364 40029 W105 D G F G G P I W S M A A N N D
Frog Xenopus laevis NP_001079449 690 77111 C420 L Y L H Q L K C E K E S L S L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648846 696 78649 R428 L K E L R I S R L K S D P L Q
Honey Bee Apis mellifera XP_393722 521 58257 T263 V R S F C K I T M K S S G R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784358 747 83111 L473 L S E K P V K L L E L R A K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06679 776 87783 N483 K L V K F I D N S K I V I C S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 80.4 91.1 N.A. 89.9 N.A. N.A. 60.4 32.6 55 N.A. N.A. 25.2 27.7 N.A. 27
Protein Similarity: 100 88.2 82.2 94.5 N.A. 95.1 N.A. N.A. 75.8 41.8 73.9 N.A. N.A. 47.1 43 N.A. 45.3
P-Site Identity: 100 0 0 0 N.A. 80 N.A. N.A. 6.6 6.6 0 N.A. N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 26.6 6.6 6.6 N.A. 80 N.A. N.A. 20 33.3 0 N.A. N.A. 6.6 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 0 0 0 9 9 9 9 0 % A
% Cys: 0 0 0 0 9 0 0 9 0 0 0 0 0 9 0 % C
% Asp: 17 9 0 0 0 0 9 0 0 0 0 9 0 0 25 % D
% Glu: 0 0 17 0 0 0 0 0 9 9 17 0 25 9 9 % E
% Phe: 0 0 9 9 25 17 9 9 0 0 0 0 0 0 9 % F
% Gly: 0 9 0 9 9 0 0 0 0 0 0 9 9 0 0 % G
% His: 9 0 9 9 9 0 9 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 9 0 25 17 0 0 0 9 0 9 0 0 % I
% Lys: 9 9 0 17 0 9 17 0 0 42 17 9 0 9 0 % K
% Leu: 25 9 9 25 0 25 17 17 42 17 9 9 9 9 9 % L
% Met: 0 0 0 0 0 0 0 0 9 17 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 0 0 9 0 17 17 9 % N
% Pro: 0 0 0 0 9 9 0 9 0 0 0 0 17 0 9 % P
% Gln: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 9 % Q
% Arg: 0 9 9 17 9 9 9 17 17 0 9 9 0 17 0 % R
% Ser: 0 25 25 0 17 0 9 0 17 9 17 17 0 9 9 % S
% Thr: 17 9 9 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 9 9 9 9 9 9 0 0 9 0 0 9 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 0 17 0 9 9 17 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _