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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIRH1A All Species: 23.94
Human Site: Y560 Identified Species: 47.88
UniProt: Q969X6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969X6 NP_116219.2 686 76890 Y560 Y S I P D K Q Y T D W S R T V
Chimpanzee Pan troglodytes XP_511062 775 86288 Y649 Y S I P D K Q Y T D W S R T V
Rhesus Macaque Macaca mulatta XP_001093408 648 72498 F534 R T V Q K Q G F H H L W L Q R
Dog Lupus familis XP_546858 699 78752 Y573 Y S I P D K Q Y T E W S R T I
Cat Felis silvestris
Mouse Mus musculus Q8R2N2 686 76891 Y560 F S I P E K Q Y T E W S R S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510337 754 84989 Y628 F S I P Q K Q Y T E W S R K I
Chicken Gallus gallus XP_001232920 364 40029 E249 S L A V S E K E D S I V V G T
Frog Xenopus laevis NP_001079449 690 77111 Y564 F N I T Q R Q Y T E W G R R V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648846 696 78649 F572 Y D L V N R I F T C E T N E Y
Honey Bee Apis mellifera XP_393722 521 58257 V407 S T D S H V R V F N F D V I E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784358 747 83111 Y617 Y D I T K H E Y T P W S R S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06679 776 87783 K627 D N L P K E W K T L K E N C V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 80.4 91.1 N.A. 89.9 N.A. N.A. 60.4 32.6 55 N.A. N.A. 25.2 27.7 N.A. 27
Protein Similarity: 100 88.2 82.2 94.5 N.A. 95.1 N.A. N.A. 75.8 41.8 73.9 N.A. N.A. 47.1 43 N.A. 45.3
P-Site Identity: 100 100 0 86.6 N.A. 66.6 N.A. N.A. 66.6 0 46.6 N.A. N.A. 13.3 0 N.A. 53.3
P-Site Similarity: 100 100 26.6 100 N.A. 100 N.A. N.A. 86.6 13.3 73.3 N.A. N.A. 46.6 26.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % C
% Asp: 9 17 9 0 25 0 0 0 9 17 0 9 0 0 0 % D
% Glu: 0 0 0 0 9 17 9 9 0 34 9 9 0 9 9 % E
% Phe: 25 0 0 0 0 0 0 17 9 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 9 0 9 0 % G
% His: 0 0 0 0 9 9 0 0 9 9 0 0 0 0 0 % H
% Ile: 0 0 59 0 0 0 9 0 0 0 9 0 0 9 17 % I
% Lys: 0 0 0 0 25 42 9 9 0 0 9 0 0 9 0 % K
% Leu: 0 9 17 0 0 0 0 0 0 9 9 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 9 0 0 0 0 9 0 0 17 0 0 % N
% Pro: 0 0 0 50 0 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 9 17 9 50 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 0 0 0 17 9 0 0 0 0 0 59 9 9 % R
% Ser: 17 42 0 9 9 0 0 0 0 9 0 50 0 17 0 % S
% Thr: 0 17 0 17 0 0 0 0 75 0 0 9 0 25 9 % T
% Val: 0 0 9 17 0 9 0 9 0 0 0 9 17 0 42 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 59 9 0 0 0 % W
% Tyr: 42 0 0 0 0 0 0 59 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _