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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIRH1A
All Species:
13.03
Human Site:
Y621
Identified Species:
26.06
UniProt:
Q969X6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969X6
NP_116219.2
686
76890
Y621
P
N
D
K
T
L
L
Y
N
P
F
P
P
T
N
Chimpanzee
Pan troglodytes
XP_511062
775
86288
Y710
P
N
D
K
T
L
L
Y
N
P
F
P
P
T
N
Rhesus Macaque
Macaca mulatta
XP_001093408
648
72498
V595
P
T
N
E
S
D
V
V
R
R
R
T
A
H
A
Dog
Lupus familis
XP_546858
699
78752
Y634
P
N
D
K
T
L
F
Y
N
P
L
P
P
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2N2
686
76891
Y621
P
N
E
K
T
V
L
Y
N
P
L
P
P
K
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510337
754
84989
F689
P
D
D
K
S
L
L
F
N
Q
A
S
L
K
Q
Chicken
Gallus gallus
XP_001232920
364
40029
L310
S
G
G
L
D
A
Q
L
V
I
R
P
L
M
E
Frog
Xenopus laevis
NP_001079449
690
77111
V625
P
D
D
K
T
P
L
V
N
Q
I
T
L
K
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648846
696
78649
L633
S
N
S
K
S
K
K
L
S
N
G
N
R
S
S
Honey Bee
Apis mellifera
XP_393722
521
58257
Y468
K
Y
L
V
C
A
D
Y
H
G
R
I
A
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784358
747
83111
L678
P
R
A
N
E
R
L
L
A
P
R
A
G
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06679
776
87783
M688
I
T
D
E
S
N
F
M
N
D
E
E
D
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
80.4
91.1
N.A.
89.9
N.A.
N.A.
60.4
32.6
55
N.A.
N.A.
25.2
27.7
N.A.
27
Protein Similarity:
100
88.2
82.2
94.5
N.A.
95.1
N.A.
N.A.
75.8
41.8
73.9
N.A.
N.A.
47.1
43
N.A.
45.3
P-Site Identity:
100
100
6.6
86.6
N.A.
73.3
N.A.
N.A.
40
6.6
40
N.A.
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
33.3
86.6
N.A.
86.6
N.A.
N.A.
60
6.6
53.3
N.A.
N.A.
40
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
0
0
9
0
9
9
17
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
50
0
9
9
9
0
0
9
0
0
9
9
0
% D
% Glu:
0
0
9
17
9
0
0
0
0
0
9
9
0
0
17
% E
% Phe:
0
0
0
0
0
0
17
9
0
0
17
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
9
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
9
9
0
0
0
% I
% Lys:
9
0
0
59
0
9
9
0
0
0
0
0
0
34
0
% K
% Leu:
0
0
9
9
0
34
50
25
0
0
17
0
25
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% M
% Asn:
0
42
9
9
0
9
0
0
59
9
0
9
0
0
34
% N
% Pro:
67
0
0
0
0
9
0
0
0
42
0
42
34
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
17
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
9
0
0
9
9
34
0
9
0
9
% R
% Ser:
17
0
9
0
34
0
0
0
9
0
0
9
0
9
9
% S
% Thr:
0
17
0
0
42
0
0
0
0
0
0
17
0
25
0
% T
% Val:
0
0
0
9
0
9
9
17
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
42
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _