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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC2 All Species: 13.64
Human Site: S137 Identified Species: 25
UniProt: Q969Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969Z3 NP_060368.2 335 38023 S137 M D Q L V L P S K Q P S S N K
Chimpanzee Pan troglodytes XP_001172871 335 37950 S137 M D Q L V L P S K Q P S S N K
Rhesus Macaque Macaca mulatta XP_001102382 335 37830 S137 M D Q L V L P S K Q P S S N K
Dog Lupus familis XP_536125 436 46635 C234 L G R H L S A C Q G R T V T L
Cat Felis silvestris
Mouse Mus musculus Q922Q1 338 38176 I137 M E Q I V L P I K L P S S N K
Rat Rattus norvegicus O88994 338 38230 I137 M E P I V L P I K L P S S N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511805 330 36593 S132 R E D L S L P S K L P A T N T
Chicken Gallus gallus XP_426119 334 37265 V135 M K K L C L P V K L P S K N P
Frog Xenopus laevis Q5U534 343 38202 L140 M Q E V Q I P L P L P K S N R
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 P129 Q M E E L K F P L N N S S D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 S123 A P G M I S L S I D L S R I Q
Nematode Worm Caenorhab. elegans NP_499948 340 38753 N134 K I E D V K A N K D L R S G F
Sea Urchin Strong. purpuratus XP_781060 330 36744 L124 M P T L T V P L I S D L R G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 41.9 N.A. 74.5 73.9 N.A. 61.7 60.5 46.6 44.7 N.A. N.A. 38.7 32.9 35.5
Protein Similarity: 100 99.4 97.6 56.8 N.A. 89.3 89.3 N.A. 75.2 74.6 67.3 65.6 N.A. N.A. 53.3 51.1 58.2
P-Site Identity: 100 100 100 0 N.A. 73.3 66.6 N.A. 46.6 53.3 33.3 13.3 N.A. N.A. 13.3 20 20
P-Site Similarity: 100 100 100 33.3 N.A. 86.6 80 N.A. 66.6 60 60 33.3 N.A. N.A. 33.3 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 16 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 24 8 8 0 0 0 0 0 16 8 0 0 8 0 % D
% Glu: 0 24 24 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 8 8 0 0 0 0 0 0 8 0 0 0 16 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 16 8 8 0 16 16 0 0 0 0 8 0 % I
% Lys: 8 8 8 0 0 16 0 0 62 0 0 8 8 0 39 % K
% Leu: 8 0 0 47 16 54 8 16 8 39 16 8 0 0 16 % L
% Met: 62 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 8 0 0 62 0 % N
% Pro: 0 16 8 0 0 0 70 8 8 0 62 0 0 0 8 % P
% Gln: 8 8 31 0 8 0 0 0 8 24 0 0 0 0 8 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 8 8 16 0 16 % R
% Ser: 0 0 0 0 8 16 0 39 0 8 0 62 62 0 0 % S
% Thr: 0 0 8 0 8 0 0 0 0 0 0 8 8 8 8 % T
% Val: 0 0 0 8 47 8 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _