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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOSC2
All Species:
26.97
Human Site:
S142
Identified Species:
49.44
UniProt:
Q969Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969Z3
NP_060368.2
335
38023
S142
L
P
S
K
Q
P
S
S
N
K
L
H
N
C
R
Chimpanzee
Pan troglodytes
XP_001172871
335
37950
S142
L
P
S
K
Q
P
S
S
N
K
L
H
K
C
R
Rhesus Macaque
Macaca mulatta
XP_001102382
335
37830
S142
L
P
S
K
Q
P
S
S
N
K
L
H
N
C
R
Dog
Lupus familis
XP_536125
436
46635
V239
S
A
C
Q
G
R
T
V
T
L
A
L
S
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q1
338
38176
S142
L
P
I
K
L
P
S
S
N
K
I
H
N
C
R
Rat
Rattus norvegicus
O88994
338
38230
S142
L
P
I
K
L
P
S
S
N
K
I
H
D
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511805
330
36593
T137
L
P
S
K
L
P
A
T
N
T
V
L
D
C
R
Chicken
Gallus gallus
XP_426119
334
37265
K140
L
P
V
K
L
P
S
K
N
P
V
Q
N
C
R
Frog
Xenopus laevis
Q5U534
343
38202
S145
I
P
L
P
L
P
K
S
N
R
V
L
D
C
R
Zebra Danio
Brachydanio rerio
Q58EJ9
325
36698
S134
K
F
P
L
N
N
S
S
D
L
V
V
D
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120819
341
38547
R128
S
L
S
I
D
L
S
R
I
Q
G
K
G
F
R
Nematode Worm
Caenorhab. elegans
NP_499948
340
38753
S139
K
A
N
K
D
L
R
S
G
F
L
H
V
D
L
Sea Urchin
Strong. purpuratus
XP_781060
330
36744
R129
V
P
L
I
S
D
L
R
G
R
V
F
N
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.2
41.9
N.A.
74.5
73.9
N.A.
61.7
60.5
46.6
44.7
N.A.
N.A.
38.7
32.9
35.5
Protein Similarity:
100
99.4
97.6
56.8
N.A.
89.3
89.3
N.A.
75.2
74.6
67.3
65.6
N.A.
N.A.
53.3
51.1
58.2
P-Site Identity:
100
93.3
100
6.6
N.A.
80
73.3
N.A.
53.3
60
40
26.6
N.A.
N.A.
20
26.6
20
P-Site Similarity:
100
93.3
100
26.6
N.A.
86.6
86.6
N.A.
80
66.6
66.6
46.6
N.A.
N.A.
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
77
0
% C
% Asp:
0
0
0
0
16
8
0
0
8
0
0
0
31
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
0
8
0
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
16
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% H
% Ile:
8
0
16
16
0
0
0
0
8
0
16
0
0
0
0
% I
% Lys:
16
0
0
62
0
0
8
8
0
39
0
8
8
0
0
% K
% Leu:
54
8
16
8
39
16
8
0
0
16
31
24
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
0
62
0
0
0
39
0
0
% N
% Pro:
0
70
8
8
0
62
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
24
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
16
0
16
0
0
0
0
85
% R
% Ser:
16
0
39
0
8
0
62
62
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
8
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
8
0
0
39
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _