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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC2 All Species: 37.27
Human Site: S295 Identified Species: 68.33
UniProt: Q969Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969Z3 NP_060368.2 335 38023 S295 Q P L D T L K S Y R L C D P S
Chimpanzee Pan troglodytes XP_001172871 335 37950 S295 Q P L D T L K S Y R L C D P S
Rhesus Macaque Macaca mulatta XP_001102382 335 37830 S295 E P L D T L K S Y R L C D P S
Dog Lupus familis XP_536125 436 46635 S395 E P L E T L K S Y R L C D P S
Cat Felis silvestris
Mouse Mus musculus Q922Q1 338 38176 S297 E P L E T L K S Y R L C D P S
Rat Rattus norvegicus O88994 338 38230 S297 E P L E T L K S Y R L C D P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511805 330 36593 S290 E P L E T L K S Y R L C D P S
Chicken Gallus gallus XP_426119 334 37265 S293 E P L E T L K S Y R L C D P S
Frog Xenopus laevis Q5U534 343 38202 T300 E P L D T L R T F R Q S D S S
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 T285 S R K E P L E T L K T Y R M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 K287 A E P L K T L K S Y R Q I M D
Nematode Worm Caenorhab. elegans NP_499948 340 38753 R294 M Q P L K K L R E F R L G P G
Sea Urchin Strong. purpuratus XP_781060 330 36744 R289 L K T L R T Y R M A T P D D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 41.9 N.A. 74.5 73.9 N.A. 61.7 60.5 46.6 44.7 N.A. N.A. 38.7 32.9 35.5
Protein Similarity: 100 99.4 97.6 56.8 N.A. 89.3 89.3 N.A. 75.2 74.6 67.3 65.6 N.A. N.A. 53.3 51.1 58.2
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 86.6 86.6 53.3 6.6 N.A. N.A. 0 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 80 40 N.A. N.A. 0 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 62 0 0 0 % C
% Asp: 0 0 0 31 0 0 0 0 0 0 0 0 77 8 8 % D
% Glu: 54 8 0 47 0 0 8 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 8 0 16 8 62 8 0 8 0 0 0 0 0 % K
% Leu: 8 0 70 24 0 77 16 0 8 0 62 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 8 0 0 0 0 16 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 70 16 0 8 0 0 0 0 0 0 8 0 70 8 % P
% Gln: 16 8 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 8 0 0 8 0 8 16 0 70 16 0 8 0 0 % R
% Ser: 8 0 0 0 0 0 0 62 8 0 0 8 0 8 70 % S
% Thr: 0 0 8 0 70 16 0 16 0 0 16 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 62 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _