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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC2 All Species: 28.18
Human Site: S310 Identified Species: 51.67
UniProt: Q969Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969Z3 NP_060368.2 335 38023 S310 E R E L Y K L S P L F G I Y Y
Chimpanzee Pan troglodytes XP_001172871 335 37950 S310 E R E L Y K L S P L F G I Y Y
Rhesus Macaque Macaca mulatta XP_001102382 335 37830 S310 E R E L Y K L S P L F G I Y Y
Dog Lupus familis XP_536125 436 46635 S410 E K Q I Y K S S P L F G I Y Y
Cat Felis silvestris
Mouse Mus musculus Q922Q1 338 38176 S312 V K S I Y Q S S P L F G M Y F
Rat Rattus norvegicus O88994 338 38230 S312 V K S L Y Q S S P L F G M Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511805 330 36593 S305 E R H I H K T S P L F G M Y F
Chicken Gallus gallus XP_426119 334 37265 S308 E R H I Y K S S P L F G K Y F
Frog Xenopus laevis Q5U534 343 38202 A315 L K E V Y K N A P L F G Q Y Y
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 P300 D P K Q K T S P I L G Q Y Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 G302 P I I R P L V G E S P V L G I
Nematode Worm Caenorhab. elegans NP_499948 340 38753 E309 K L R Q E F G E S P I F G V N
Sea Urchin Strong. purpuratus XP_781060 330 36744 N304 D Q K T Y G A N P V F G T N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 41.9 N.A. 74.5 73.9 N.A. 61.7 60.5 46.6 44.7 N.A. N.A. 38.7 32.9 35.5
Protein Similarity: 100 99.4 97.6 56.8 N.A. 89.3 89.3 N.A. 75.2 74.6 67.3 65.6 N.A. N.A. 53.3 51.1 58.2
P-Site Identity: 100 100 100 73.3 N.A. 46.6 53.3 N.A. 60 66.6 60 13.3 N.A. N.A. 0 0 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 86.6 80 80 26.6 N.A. N.A. 13.3 6.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 47 0 31 0 8 0 0 8 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 77 8 0 0 31 % F
% Gly: 0 0 0 0 0 8 8 8 0 0 8 77 8 8 0 % G
% His: 0 0 16 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 31 0 0 0 0 8 0 8 0 31 0 8 % I
% Lys: 8 31 16 0 8 54 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 8 0 31 0 8 24 0 0 77 0 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % M
% Asn: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 8 % N
% Pro: 8 8 0 0 8 0 0 8 77 8 8 0 0 0 0 % P
% Gln: 0 8 8 16 0 16 0 0 0 0 0 8 8 0 0 % Q
% Arg: 0 39 8 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 16 0 0 0 39 62 8 8 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 8 8 0 0 0 0 0 8 0 8 % T
% Val: 16 0 0 8 0 0 8 0 0 8 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 70 0 0 0 0 0 0 0 8 77 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _