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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOSC2
All Species:
13.33
Human Site:
T197
Identified Species:
24.44
UniProt:
Q969Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969Z3
NP_060368.2
335
38023
T197
T
S
R
K
L
L
P
T
L
D
Q
N
F
Q
V
Chimpanzee
Pan troglodytes
XP_001172871
335
37950
T197
T
S
R
K
L
L
P
T
L
D
Q
N
F
Q
V
Rhesus Macaque
Macaca mulatta
XP_001102382
335
37830
T197
T
S
R
K
L
L
P
T
L
D
Q
N
Y
Q
V
Dog
Lupus familis
XP_536125
436
46635
P297
P
S
K
E
I
F
S
P
V
V
P
N
Y
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q1
338
38176
S197
T
T
K
K
L
Y
P
S
E
S
Y
L
Q
N
Y
Rat
Rattus norvegicus
O88994
338
38230
S197
T
T
K
K
L
Y
P
S
E
S
Y
L
Q
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511805
330
36593
Q192
Q
S
K
D
L
I
S
Q
L
V
T
D
Y
Q
V
Chicken
Gallus gallus
XP_426119
334
37265
L195
K
S
K
D
I
I
N
L
F
R
T
T
D
E
V
Frog
Xenopus laevis
Q5U534
343
38202
L202
Q
S
K
K
K
E
K
L
F
R
D
K
D
V
I
Zebra Danio
Brachydanio rerio
Q58EJ9
325
36698
L190
R
P
H
E
K
E
P
L
F
P
K
D
D
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120819
341
38547
L189
R
K
S
N
R
Q
W
L
L
T
P
D
D
T
G
Nematode Worm
Caenorhab. elegans
NP_499948
340
38753
G190
R
T
C
K
T
E
E
G
W
W
N
N
E
V
P
Sea Urchin
Strong. purpuratus
XP_781060
330
36744
K187
N
D
R
K
W
G
S
K
S
K
H
G
E
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.2
41.9
N.A.
74.5
73.9
N.A.
61.7
60.5
46.6
44.7
N.A.
N.A.
38.7
32.9
35.5
Protein Similarity:
100
99.4
97.6
56.8
N.A.
89.3
89.3
N.A.
75.2
74.6
67.3
65.6
N.A.
N.A.
53.3
51.1
58.2
P-Site Identity:
100
100
93.3
26.6
N.A.
26.6
26.6
N.A.
33.3
13.3
13.3
13.3
N.A.
N.A.
6.6
13.3
13.3
P-Site Similarity:
100
100
100
60
N.A.
46.6
46.6
N.A.
60
40
26.6
40
N.A.
N.A.
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
16
0
0
0
0
0
24
8
24
31
0
0
% D
% Glu:
0
0
0
16
0
24
8
0
16
0
0
0
16
16
0
% E
% Phe:
0
0
0
0
0
8
0
0
24
0
0
0
16
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
16
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
16
16
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
47
62
16
0
8
8
0
8
8
8
0
8
0
% K
% Leu:
0
0
0
0
47
24
0
31
39
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
0
0
0
8
39
0
16
0
% N
% Pro:
8
8
0
0
0
0
47
8
0
8
16
0
0
0
8
% P
% Gln:
16
0
0
0
0
8
0
8
0
0
24
0
16
39
0
% Q
% Arg:
24
0
31
0
8
0
0
0
0
16
0
0
0
0
0
% R
% Ser:
0
54
8
0
0
0
24
16
8
16
0
0
0
0
0
% S
% Thr:
39
24
0
0
8
0
0
24
0
8
16
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
8
16
0
0
0
16
54
% V
% Trp:
0
0
0
0
8
0
8
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
16
0
24
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _