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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOSC2
All Species:
36.97
Human Site:
T225
Identified Species:
67.78
UniProt:
Q969Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969Z3
NP_060368.2
335
38023
T225
A
S
L
V
D
L
N
T
R
M
E
K
K
M
K
Chimpanzee
Pan troglodytes
XP_001172871
335
37950
T225
A
S
L
V
D
L
N
T
R
M
E
K
K
M
K
Rhesus Macaque
Macaca mulatta
XP_001102382
335
37830
T225
A
S
L
V
D
L
N
T
R
I
E
K
K
M
K
Dog
Lupus familis
XP_536125
436
46635
T325
A
S
L
A
D
L
N
T
R
L
E
K
K
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q1
338
38176
L225
S
E
A
S
L
V
D
L
N
T
R
L
K
K
K
Rat
Rattus norvegicus
O88994
338
38230
L225
S
E
A
S
L
V
D
L
N
T
R
L
Q
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511805
330
36593
S220
A
S
L
A
D
L
N
S
R
L
E
K
K
V
S
Chicken
Gallus gallus
XP_426119
334
37265
T223
A
S
L
K
D
L
N
T
R
L
E
K
K
V
K
Frog
Xenopus laevis
Q5U534
343
38202
S230
T
S
M
E
A
L
N
S
R
L
E
Q
P
V
S
Zebra Danio
Brachydanio rerio
Q58EJ9
325
36698
S218
A
S
V
G
D
L
N
S
R
L
D
K
D
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120819
341
38547
T217
A
S
V
T
D
L
N
T
R
L
E
K
P
V
N
Nematode Worm
Caenorhab. elegans
NP_499948
340
38753
S218
Y
M
I
T
S
Q
A
S
L
D
D
L
N
S
K
Sea Urchin
Strong. purpuratus
XP_781060
330
36744
S215
T
S
L
I
N
L
N
S
K
L
D
Q
Q
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.2
41.9
N.A.
74.5
73.9
N.A.
61.7
60.5
46.6
44.7
N.A.
N.A.
38.7
32.9
35.5
Protein Similarity:
100
99.4
97.6
56.8
N.A.
89.3
89.3
N.A.
75.2
74.6
67.3
65.6
N.A.
N.A.
53.3
51.1
58.2
P-Site Identity:
100
100
93.3
80
N.A.
13.3
6.6
N.A.
66.6
80
33.3
46.6
N.A.
N.A.
60
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
86.6
93.3
66.6
80
N.A.
N.A.
80
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
16
16
8
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
62
0
16
0
0
8
24
0
8
0
0
% D
% Glu:
0
16
0
8
0
0
0
0
0
0
62
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
0
62
54
16
62
% K
% Leu:
0
0
54
0
16
77
0
16
8
54
0
24
0
16
0
% L
% Met:
0
8
8
0
0
0
0
0
0
16
0
0
0
24
0
% M
% Asn:
0
0
0
0
8
0
77
0
16
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
16
16
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
70
0
16
0
0
0
0
% R
% Ser:
16
77
0
16
8
0
0
39
0
0
0
0
0
8
24
% S
% Thr:
16
0
0
16
0
0
0
47
0
16
0
0
0
0
0
% T
% Val:
0
0
16
24
0
16
0
0
0
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _