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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC2 All Species: 42.12
Human Site: T281 Identified Species: 77.22
UniProt: Q969Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969Z3 NP_060368.2 335 38023 T281 L T T V D P D T G V I D R K Q
Chimpanzee Pan troglodytes XP_001172871 335 37950 T281 L T T V D P D T G V I D R K Q
Rhesus Macaque Macaca mulatta XP_001102382 335 37830 T281 L T T V D P D T G V I D R K E
Dog Lupus familis XP_536125 436 46635 T381 L T T V D P D T G I I D R K E
Cat Felis silvestris
Mouse Mus musculus Q922Q1 338 38176 T283 L T T V D P D T G I I D R K E
Rat Rattus norvegicus O88994 338 38230 T283 L T T V D P D T G I I D R K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511805 330 36593 T276 L T T V D P D T G I I S R K E
Chicken Gallus gallus XP_426119 334 37265 T279 L T T V D P D T G V L D R K E
Frog Xenopus laevis Q5U534 343 38202 S286 L T T V N P N S G V I T R K E
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 D271 R C L F T T V D P E T G V F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 T273 F T T V D P E T G T K N P K A
Nematode Worm Caenorhab. elegans NP_499948 340 38753 T280 L T T V N P E T G T K D K D M
Sea Urchin Strong. purpuratus XP_781060 330 36744 F275 V D P N T G K F M E T K E P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 41.9 N.A. 74.5 73.9 N.A. 61.7 60.5 46.6 44.7 N.A. N.A. 38.7 32.9 35.5
Protein Similarity: 100 99.4 97.6 56.8 N.A. 89.3 89.3 N.A. 75.2 74.6 67.3 65.6 N.A. N.A. 53.3 51.1 58.2
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 80 86.6 66.6 0 N.A. N.A. 53.3 53.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 100 93.3 0 N.A. N.A. 66.6 73.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 70 0 62 8 0 0 0 62 0 8 0 % D
% Glu: 0 0 0 0 0 0 16 0 0 16 0 0 8 0 54 % E
% Phe: 8 0 0 8 0 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 8 0 0 85 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 31 62 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 16 8 8 77 0 % K
% Leu: 77 0 8 0 0 0 0 0 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 16 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 8 0 0 85 0 0 8 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 70 0 0 % R
% Ser: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 8 % S
% Thr: 0 85 85 0 16 8 0 77 0 16 16 8 0 0 0 % T
% Val: 8 0 0 85 0 0 8 0 0 39 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _