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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOSC2 All Species: 24.85
Human Site: Y206 Identified Species: 45.56
UniProt: Q969Z3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969Z3 NP_060368.2 335 38023 Y206 D Q N F Q V A Y P D Y C P L L
Chimpanzee Pan troglodytes XP_001172871 335 37950 Y206 D Q N F Q V A Y P D Y C P L L
Rhesus Macaque Macaca mulatta XP_001102382 335 37830 Y206 D Q N Y Q V A Y P D C S P L L
Dog Lupus familis XP_536125 436 46635 Y306 V P N Y Q V A Y P D C S P I M
Cat Felis silvestris
Mouse Mus musculus Q922Q1 338 38176 V206 S Y L Q N Y E V A Y P D C S P
Rat Rattus norvegicus O88994 338 38230 V206 S Y L Q N Y E V A Y P D C S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511805 330 36593 Y201 V T D Y Q V A Y P D C S P I N
Chicken Gallus gallus XP_426119 334 37265 Y204 R T T D E V A Y P D C S P L L
Frog Xenopus laevis Q5U534 343 38202 Y211 R D K D V I A Y P D A S P I M
Zebra Danio Brachydanio rerio Q58EJ9 325 36698 Y199 P K D D E V A Y P D A A P V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120819 341 38547 Y198 T P D D T G A Y P D A T S Y C
Nematode Worm Caenorhab. elegans NP_499948 340 38753 R199 W N N E V P K R I D D T A Y A
Sea Urchin Strong. purpuratus XP_781060 330 36744 F196 K H G E K G M F Q N L A H L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 41.9 N.A. 74.5 73.9 N.A. 61.7 60.5 46.6 44.7 N.A. N.A. 38.7 32.9 35.5
Protein Similarity: 100 99.4 97.6 56.8 N.A. 89.3 89.3 N.A. 75.2 74.6 67.3 65.6 N.A. N.A. 53.3 51.1 58.2
P-Site Identity: 100 100 80 53.3 N.A. 0 0 N.A. 46.6 53.3 33.3 40 N.A. N.A. 26.6 13.3 6.6
P-Site Similarity: 100 100 86.6 73.3 N.A. 0 0 N.A. 66.6 60 53.3 73.3 N.A. N.A. 33.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 70 0 16 0 24 16 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 31 16 16 0 8 % C
% Asp: 24 8 24 31 0 0 0 0 0 77 8 16 0 0 0 % D
% Glu: 0 0 0 16 16 0 16 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 16 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 16 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 24 0 % I
% Lys: 8 8 8 0 8 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 16 0 0 0 0 0 0 0 8 0 0 39 31 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 24 % M
% Asn: 0 8 39 0 16 0 0 0 0 8 0 0 0 0 8 % N
% Pro: 8 16 0 0 0 8 0 0 70 0 16 0 62 0 16 % P
% Gln: 0 24 0 16 39 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 16 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 16 0 0 0 0 0 0 0 0 0 0 39 8 16 0 % S
% Thr: 8 16 8 0 8 0 0 0 0 0 0 16 0 0 0 % T
% Val: 16 0 0 0 16 54 0 16 0 0 0 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 24 0 16 0 70 0 16 16 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _