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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1E2
All Species:
23.03
Human Site:
S103
Identified Species:
42.22
UniProt:
Q96A05
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A05
NP_542384.1
226
26074
S103
S
E
A
K
L
R
L
S
R
I
V
E
D
P
E
Chimpanzee
Pan troglodytes
XP_525751
226
26056
S103
S
E
A
K
L
R
L
S
R
I
V
E
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001113068
226
26042
S103
S
E
A
K
L
R
L
S
R
I
V
E
N
P
E
Dog
Lupus familis
XP_538480
226
25942
S103
N
D
A
K
L
R
L
S
R
I
V
A
D
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P50518
226
26139
S103
N
E
A
K
Q
R
L
S
K
V
V
K
D
T
T
Rat
Rattus norvegicus
Q6PCU2
226
26110
S103
N
E
A
K
Q
R
L
S
K
V
V
K
D
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006246
226
26100
A103
N
E
A
K
L
R
L
A
K
V
V
K
D
T
A
Frog
Xenopus laevis
NP_001079767
226
25885
A103
N
E
A
R
Q
R
L
A
R
V
V
K
D
T
A
Zebra Danio
Brachydanio rerio
NP_775361
226
25892
A103
N
D
A
R
Q
R
L
A
N
V
A
R
D
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54611
226
26064
G103
D
D
A
R
K
R
L
G
E
V
T
K
N
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39258
230
26041
L101
D
Q
A
A
K
D
L
L
N
V
S
R
D
E
Y
Baker's Yeast
Sacchar. cerevisiae
P22203
233
26453
S108
E
E
T
K
E
K
L
S
G
I
A
N
N
R
D
Red Bread Mold
Neurospora crassa
Q01278
230
25730
G107
E
A
A
S
A
Q
L
G
Q
A
T
H
D
L
G
Conservation
Percent
Protein Identity:
100
98.6
97.3
88.5
N.A.
77.4
77.4
N.A.
N.A.
72.5
73.4
66.3
N.A.
60.6
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.1
95.1
N.A.
86.7
86.7
N.A.
N.A.
85.8
85.8
82.3
N.A.
76.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
53.3
53.3
N.A.
N.A.
53.3
46.6
33.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
86.6
80
66.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
34.7
40
Protein Similarity:
N.A.
N.A.
N.A.
61.7
58.8
57.3
P-Site Identity:
N.A.
N.A.
N.A.
20
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
93
8
8
0
0
24
0
8
16
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
24
0
0
0
8
0
0
0
0
0
0
77
0
8
% D
% Glu:
16
62
0
0
8
0
0
0
8
0
0
24
0
8
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
39
0
0
0
0
0
% I
% Lys:
0
0
0
62
16
8
0
0
24
0
0
39
0
0
0
% K
% Leu:
0
0
0
0
39
0
100
8
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
16
0
0
8
24
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% P
% Gln:
0
8
0
0
31
8
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
24
0
77
0
0
39
0
0
16
0
8
0
% R
% Ser:
24
0
0
8
0
0
0
54
0
0
8
0
0
0
16
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
16
0
0
31
16
% T
% Val:
0
0
0
0
0
0
0
0
0
54
62
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _