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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1E2
All Species:
14.85
Human Site:
S185
Identified Species:
27.22
UniProt:
Q96A05
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A05
NP_542384.1
226
26074
S185
A
G
G
V
E
V
Y
S
G
N
Q
R
I
K
V
Chimpanzee
Pan troglodytes
XP_525751
226
26056
S185
A
G
G
V
E
V
Y
S
G
N
Q
R
I
K
V
Rhesus Macaque
Macaca mulatta
XP_001113068
226
26042
S185
A
G
G
V
E
V
Y
S
G
N
Q
R
I
K
V
Dog
Lupus familis
XP_538480
226
25942
S185
A
G
G
V
E
V
Y
S
G
N
Q
R
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P50518
226
26139
N185
A
G
G
V
E
I
Y
N
G
D
R
K
I
K
V
Rat
Rattus norvegicus
Q6PCU2
226
26110
N185
A
G
G
V
E
I
Y
N
G
D
R
K
I
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006246
226
26100
N185
A
G
G
V
E
I
Y
N
S
D
G
K
I
K
V
Frog
Xenopus laevis
NP_001079767
226
25885
N185
A
G
G
V
E
L
Y
N
G
N
G
K
I
K
V
Zebra Danio
Brachydanio rerio
NP_775361
226
25892
N185
S
G
G
I
E
L
Y
N
A
D
G
K
I
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54611
226
26064
A185
C
G
G
V
E
L
L
A
L
N
G
R
I
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39258
230
26041
T168
A
P
E
V
A
V
D
T
K
I
F
L
P
P
P
Baker's Yeast
Sacchar. cerevisiae
P22203
233
26453
N192
S
G
G
V
V
V
S
N
A
S
D
K
I
E
I
Red Bread Mold
Neurospora crassa
Q01278
230
25730
G189
A
G
G
I
I
I
V
G
G
N
G
K
I
D
I
Conservation
Percent
Protein Identity:
100
98.6
97.3
88.5
N.A.
77.4
77.4
N.A.
N.A.
72.5
73.4
66.3
N.A.
60.6
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.1
95.1
N.A.
86.7
86.7
N.A.
N.A.
85.8
85.8
82.3
N.A.
76.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
66.6
66.6
N.A.
N.A.
60
73.3
46.6
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
86.6
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
34.7
40
Protein Similarity:
N.A.
N.A.
N.A.
61.7
58.8
57.3
P-Site Identity:
N.A.
N.A.
N.A.
20
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
0
8
0
0
8
16
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
31
8
0
0
8
0
% D
% Glu:
0
0
8
0
77
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
93
93
0
0
0
0
8
62
0
39
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
8
31
0
0
0
8
0
0
93
0
16
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
54
0
77
0
% K
% Leu:
0
0
0
0
0
24
8
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
47
0
54
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
16
39
0
0
0
% R
% Ser:
16
0
0
0
0
0
8
31
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
85
8
47
8
0
0
0
0
0
0
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _