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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF166
All Species:
32.73
Human Site:
Y218
Identified Species:
72
UniProt:
Q96A37
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A37
NP_849163.1
237
26122
Y218
S
Y
D
T
F
V
D
Y
S
I
D
E
E
A
A
Chimpanzee
Pan troglodytes
Q6J212
228
25690
Y209
S
Y
D
T
F
V
D
Y
D
V
D
E
E
D
M
Rhesus Macaque
Macaca mulatta
XP_001099780
241
26223
Y222
C
A
G
P
V
P
D
Y
S
I
D
E
E
A
A
Dog
Lupus familis
XP_851172
237
26024
Y218
S
Y
D
T
F
V
D
Y
S
I
D
E
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET26
229
25727
Y210
S
Y
D
T
F
V
D
Y
D
V
D
E
D
D
M
Rat
Rattus norvegicus
Q6J1I7
237
26046
Y218
S
Y
D
T
F
V
D
Y
S
I
D
E
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514759
256
28145
Y237
S
Y
D
T
F
V
D
Y
S
I
D
E
E
A
S
Chicken
Gallus gallus
Q5F3B2
244
26625
Y225
S
Y
D
T
F
V
D
Y
N
I
D
E
E
A
A
Frog
Xenopus laevis
Q3KPU8
241
26755
Y222
S
Y
D
T
F
V
D
Y
S
I
D
E
E
A
A
Zebra Danio
Brachydanio rerio
Q7T321
383
42029
A287
M
T
E
S
N
P
L
A
S
H
S
S
Q
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785146
192
21660
N174
Y
D
T
Y
V
D
Y
N
K
E
E
D
D
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
85.4
94.9
N.A.
44.2
98.7
N.A.
72.2
82.7
84.2
20.1
N.A.
N.A.
N.A.
N.A.
41.3
Protein Similarity:
100
59.9
87.9
97.8
N.A.
60.3
99.5
N.A.
78.5
89.3
90.8
32.1
N.A.
N.A.
N.A.
N.A.
56.5
P-Site Identity:
100
73.3
60
100
N.A.
66.6
100
N.A.
93.3
93.3
100
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
80
60
100
N.A.
80
100
N.A.
100
100
100
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
0
64
55
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
73
0
0
10
82
0
19
0
82
10
19
19
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
10
82
73
0
0
% E
% Phe:
0
0
0
0
73
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
73
0
0
10
0
0
0
0
64
0
10
10
0
0
10
% S
% Thr:
0
10
10
73
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
19
73
0
0
0
19
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
73
0
10
0
0
10
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _