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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPSB4
All Species:
19.7
Human Site:
S259
Identified Species:
48.15
UniProt:
Q96A44
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A44
NP_543138.1
273
30179
S259
Q
R
L
Q
D
I
S
S
L
P
L
P
Q
S
L
Chimpanzee
Pan troglodytes
XP_525174
478
52950
T464
E
R
L
G
E
I
H
T
L
P
L
P
A
S
L
Rhesus Macaque
Macaca mulatta
XP_001113018
273
30174
S259
Q
R
L
R
D
I
S
S
L
P
L
P
Q
S
L
Dog
Lupus familis
XP_542811
273
30136
A259
Q
R
L
Q
D
I
G
A
L
P
L
P
Q
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5B6
273
30267
S259
Q
R
L
R
D
I
G
S
L
P
L
P
Q
S
L
Rat
Rattus norvegicus
Q5M877
264
28778
S250
T
R
L
G
Q
I
S
S
L
P
L
P
P
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505755
273
31164
S259
E
R
L
H
E
I
E
S
L
P
L
P
Q
S
L
Chicken
Gallus gallus
XP_426685
273
31102
I259
D
R
L
H
D
I
E
I
L
P
L
P
L
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6L9
255
28813
A237
K
L
Y
P
T
V
S
A
V
Y
G
N
T
E
V
Honey Bee
Apis mellifera
XP_392605
431
46424
A414
K
I
E
E
K
V
N
A
L
S
L
P
L
A
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
99.2
96.6
N.A.
97.8
52.7
N.A.
81.6
81.3
N.A.
N.A.
N.A.
36.2
42
N.A.
N.A.
Protein Similarity:
100
49.7
100
98.5
N.A.
99.2
66.3
N.A.
90.4
89.7
N.A.
N.A.
N.A.
51.6
52.6
N.A.
N.A.
P-Site Identity:
100
60
93.3
86.6
N.A.
86.6
60
N.A.
73.3
66.6
N.A.
N.A.
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
80
100
93.3
N.A.
93.3
73.3
N.A.
86.6
66.6
N.A.
N.A.
N.A.
40
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
30
0
0
0
0
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
10
10
20
0
20
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
20
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
20
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
80
0
10
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
80
0
0
0
0
0
90
0
90
0
20
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
80
0
90
10
0
0
% P
% Gln:
40
0
0
20
10
0
0
0
0
0
0
0
50
0
0
% Q
% Arg:
0
80
0
20
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
40
50
0
10
0
0
0
70
0
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _