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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYAP1
All Species:
16.67
Human Site:
T259
Identified Species:
40.74
UniProt:
Q96A49
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A49
NP_116185.2
352
39933
T259
V
I
K
S
Q
L
K
T
Q
E
D
E
E
E
I
Chimpanzee
Pan troglodytes
XP_520954
352
39914
T259
V
I
K
S
Q
L
K
T
Q
E
D
E
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001097183
309
35775
V229
E
I
S
T
S
P
G
V
S
E
F
V
S
D
A
Dog
Lupus familis
XP_537969
358
40467
T265
V
I
K
S
Q
L
K
T
Q
E
D
E
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V6
365
41331
S273
V
I
K
S
Q
L
K
S
Q
E
D
E
E
E
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085040
361
40999
N271
T
I
K
S
P
L
K
N
S
E
E
E
E
E
I
Zebra Danio
Brachydanio rerio
NP_957236
334
38259
T248
S
I
S
S
K
T
K
T
T
E
I
E
E
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960T2
551
56962
E408
V
I
E
P
E
A
Q
E
C
D
V
Q
A
A
K
Honey Bee
Apis mellifera
XP_001122641
259
29291
K192
E
E
V
R
E
G
M
K
K
L
G
M
Q
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780429
417
46233
E325
A
K
R
S
K
S
E
E
D
Q
L
D
I
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
84
89.1
N.A.
81.6
N.A.
N.A.
N.A.
N.A.
69.8
64.7
N.A.
28.6
29.5
N.A.
42.9
Protein Similarity:
100
99.7
85.5
93.3
N.A.
87.6
N.A.
N.A.
N.A.
N.A.
81.7
76.6
N.A.
41.9
44.5
N.A.
59.9
P-Site Identity:
100
100
13.3
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
66.6
53.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
66.6
N.A.
46.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
40
10
0
20
0
% D
% Glu:
20
10
10
0
20
0
10
20
0
70
10
60
60
60
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
80
0
0
0
0
0
0
0
0
10
0
10
0
60
% I
% Lys:
0
10
50
0
20
0
60
10
10
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
50
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
10
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
40
0
10
0
40
10
0
10
10
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
20
70
10
10
0
10
20
0
0
0
10
0
0
% S
% Thr:
10
0
0
10
0
10
0
40
10
0
0
0
0
0
10
% T
% Val:
50
0
10
0
0
0
0
10
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _