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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RERG All Species: 29.7
Human Site: S129 Identified Species: 50.26
UniProt: Q96A58 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96A58 NP_116307.1 199 22608 S129 L D H S R Q V S T E E G E K L
Chimpanzee Pan troglodytes XP_520767 199 22575 S129 L D H S R Q V S T E E G E K L
Rhesus Macaque Macaca mulatta XP_001091240 174 19965 T105 D H S R Q V S T E E G E K L A
Dog Lupus familis XP_543792 180 20254 E112 H S R Q V S T E E G E K L A T
Cat Felis silvestris
Mouse Mus musculus Q8R367 199 22561 S129 L D H S R Q V S T E E G E K L
Rat Rattus norvegicus Q62636 184 20779 N116 V P M I L V G N K C D L E D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506896 217 24867 S144 L E Q F R Q V S T E E G L S L
Chicken Gallus gallus XP_416404 199 22445 S129 L D H S R Q V S T E E G E K L
Frog Xenopus laevis Q7ZXH7 184 20815 N116 V P M I L V G N K C D L E D E
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 N116 V P M I L V G N K C D L E D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 N116 V P M V L V G N K C D L E E E
Honey Bee Apis mellifera XP_001119889 216 24087 S142 M V H L R Q V S T E E G E I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785508 209 24179 S136 L D H M R E V S T E E G E K M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P01119 309 34328 S134 L E N E R Q V S Y E D G L R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 84.4 89.9 N.A. 98.4 41.7 N.A. 38.7 95.9 41.7 41.7 N.A. 38.1 42.5 N.A. 64.5
Protein Similarity: 100 100 84.9 90.4 N.A. 100 60.7 N.A. 58.9 98.4 60.2 60.7 N.A. 61.3 54.6 N.A. 79.9
P-Site Identity: 100 100 6.6 6.6 N.A. 100 6.6 N.A. 66.6 100 6.6 6.6 N.A. 6.6 73.3 N.A. 80
P-Site Similarity: 100 100 26.6 6.6 N.A. 100 26.6 N.A. 73.3 100 26.6 26.6 N.A. 33.3 80 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % C
% Asp: 8 36 0 0 0 0 0 0 0 0 36 0 0 22 0 % D
% Glu: 0 15 0 8 0 8 0 8 15 65 58 8 72 8 29 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 29 0 0 8 8 58 0 0 0 % G
% His: 8 8 43 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 22 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 29 0 0 8 8 36 0 % K
% Leu: 50 0 0 8 29 0 0 0 0 0 0 29 22 8 50 % L
% Met: 8 0 29 8 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 8 0 0 0 0 29 0 0 0 0 0 0 0 % N
% Pro: 0 29 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 8 8 50 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 8 58 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 8 8 29 0 8 8 58 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 8 8 50 0 0 0 0 0 8 % T
% Val: 29 8 0 8 8 36 58 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _