KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC4
All Species:
20.61
Human Site:
S753
Identified Species:
41.21
UniProt:
Q96A65
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A65
NP_068579.3
974
110498
S753
N
T
D
L
P
P
V
S
E
Q
I
M
Q
T
L
Chimpanzee
Pan troglodytes
XP_001139207
974
110510
S753
N
T
D
L
P
P
V
S
E
Q
I
M
Q
T
L
Rhesus Macaque
Macaca mulatta
XP_001101461
556
63519
Q350
E
S
L
T
V
E
N
Q
P
R
L
L
L
E
L
Dog
Lupus familis
XP_539369
975
110615
S754
N
M
D
L
P
P
V
S
E
Q
I
M
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O35382
975
110526
S754
N
M
D
L
P
P
V
S
E
Q
I
M
Q
T
L
Rat
Rattus norvegicus
Q62824
975
110534
S754
N
M
D
L
P
P
V
S
E
Q
I
M
Q
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511490
951
106803
L745
S
E
V
L
I
G
N
L
G
D
K
L
I
P
Q
Chicken
Gallus gallus
XP_414996
976
111102
S755
S
M
E
N
L
P
A
S
E
Q
I
L
Q
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025305
968
109680
R747
N
S
E
S
V
R
S
R
E
Q
I
L
Q
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNH6
985
111648
K772
C
G
A
D
I
A
V
K
D
G
T
I
K
V
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWS2
893
100996
V677
M
M
L
D
T
C
M
V
Q
V
R
L
K
D
G
Sea Urchin
Strong. purpuratus
XP_796621
637
72763
P431
N
T
L
T
E
I
P
P
V
D
M
S
L
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
49.3
96.9
N.A.
95.7
95.2
N.A.
85.4
89.7
N.A.
80.4
N.A.
35.3
N.A.
27.3
33.5
Protein Similarity:
100
99.9
52.2
98.3
N.A.
97.8
97.6
N.A.
89
94.8
N.A.
88.8
N.A.
57.4
N.A.
48.9
47.6
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
6.6
53.3
N.A.
46.6
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
20
73.3
N.A.
66.6
N.A.
33.3
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
17
0
0
0
0
9
17
0
0
0
9
0
% D
% Glu:
9
9
17
0
9
9
0
0
59
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
9
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
17
9
0
0
0
0
59
9
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
9
0
17
0
0
% K
% Leu:
0
0
25
50
9
0
0
9
0
0
9
42
17
9
67
% L
% Met:
9
42
0
0
0
0
9
0
0
0
9
42
0
0
9
% M
% Asn:
59
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
42
50
9
9
9
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
59
0
0
59
0
9
% Q
% Arg:
0
0
0
0
0
9
0
9
0
9
9
0
0
0
0
% R
% Ser:
17
17
0
9
0
0
9
50
0
0
0
9
0
0
0
% S
% Thr:
0
25
0
17
9
0
0
0
0
0
9
0
0
59
0
% T
% Val:
0
0
9
0
17
0
50
9
9
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _