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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC4
All Species:
29.39
Human Site:
Y600
Identified Species:
58.79
UniProt:
Q96A65
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A65
NP_068579.3
974
110498
Y600
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Chimpanzee
Pan troglodytes
XP_001139207
974
110510
Y600
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Rhesus Macaque
Macaca mulatta
XP_001101461
556
63519
R221
L
Y
I
K
S
T
S
R
V
V
Q
R
N
K
E
Dog
Lupus familis
XP_539369
975
110615
Y601
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Cat
Felis silvestris
Mouse
Mus musculus
O35382
975
110526
Y601
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Rat
Rattus norvegicus
Q62824
975
110534
Y601
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511490
951
106803
L616
A
S
D
P
L
K
I
L
A
N
A
D
T
M
K
Chicken
Gallus gallus
XP_414996
976
111102
Y602
L
M
H
D
L
S
A
Y
S
D
Q
F
L
N
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025305
968
109680
Y594
L
M
Q
D
L
S
A
Y
S
N
Q
F
L
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNH6
985
111648
Y605
L
I
Q
D
L
P
C
Y
S
E
D
L
L
K
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWS2
893
100996
P547
D
V
Y
D
R
M
T
P
K
N
P
D
P
S
L
Sea Urchin
Strong. purpuratus
XP_796621
637
72763
A302
D
Y
K
E
T
C
Y
A
T
Y
R
G
L
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
49.3
96.9
N.A.
95.7
95.2
N.A.
85.4
89.7
N.A.
80.4
N.A.
35.3
N.A.
27.3
33.5
Protein Similarity:
100
99.9
52.2
98.3
N.A.
97.8
97.6
N.A.
89
94.8
N.A.
88.8
N.A.
57.4
N.A.
48.9
47.6
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
100
N.A.
80
N.A.
46.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
20
100
N.A.
86.6
N.A.
60
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
59
9
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
75
0
0
0
0
0
50
9
17
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
9
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
0
9
0
0
9
0
0
0
0
17
9
% K
% Leu:
75
0
0
0
75
0
0
9
0
0
0
9
75
0
9
% L
% Met:
0
59
0
0
0
9
0
0
0
0
0
0
0
9
67
% M
% Asn:
0
0
0
0
0
0
0
0
0
25
0
0
9
50
0
% N
% Pro:
0
0
0
9
0
9
0
9
0
0
9
0
9
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
67
0
0
0
9
% Q
% Arg:
0
0
0
0
9
0
0
9
0
0
9
9
0
0
0
% R
% Ser:
0
9
0
0
9
59
9
0
67
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
9
9
9
0
9
0
0
0
9
0
0
% T
% Val:
0
9
0
0
0
0
0
0
9
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
9
0
0
0
9
67
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _