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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADC
All Species:
18.79
Human Site:
T27
Identified Species:
31.79
UniProt:
Q96A70
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A70
NP_443724.1
460
49980
T27
R
D
L
L
K
E
L
T
L
G
A
S
Q
A
T
Chimpanzee
Pan troglodytes
XP_524555
420
45293
T27
R
D
L
L
K
E
L
T
L
G
A
S
Q
A
T
Rhesus Macaque
Macaca mulatta
XP_001106869
460
49820
T27
R
D
L
L
K
E
L
T
L
G
A
S
E
A
T
Dog
Lupus familis
XP_535320
460
49774
T27
R
D
L
L
E
E
L
T
L
G
A
S
Q
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVM4
459
49484
T27
R
D
L
L
E
E
L
T
L
G
A
S
Q
A
T
Rat
Rattus norvegicus
P09057
461
51029
I28
K
D
I
L
D
Q
K
I
N
E
V
S
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516497
344
37229
Chicken
Gallus gallus
P27118
450
49716
F30
S
S
D
D
K
D
A
F
Y
V
A
D
L
G
D
Frog
Xenopus laevis
Q9I8S4
456
50618
I27
R
D
L
M
E
E
I
I
N
E
V
S
Q
T
E
Zebra Danio
Brachydanio rerio
NP_571876
461
50770
I28
R
D
I
V
E
Q
K
I
N
E
S
S
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40807
394
44176
Q27
V
I
E
E
C
D
L
Q
R
L
D
Q
A
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41931
422
46901
D28
D
Q
L
Q
M
C
R
D
I
A
A
S
K
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08432
466
52267
Y32
V
T
Q
K
K
Q
Y
Y
K
D
G
E
T
L
H
Red Bread Mold
Neurospora crassa
P27121
484
53282
I61
K
L
V
A
K
Q
M
I
G
D
A
L
R
Q
R
Conservation
Percent
Protein Identity:
100
78.4
97.3
88.2
N.A.
86
49
N.A.
50.6
49.3
60
50.5
N.A.
35
N.A.
31.5
N.A.
Protein Similarity:
100
81.7
98.4
93
N.A.
92.6
70.9
N.A.
61.2
68.9
77.1
70.5
N.A.
52.8
N.A.
54.1
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
0
13.3
40
20
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
0
20
60
60
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
8
58
0
8
36
0
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
58
8
8
8
15
0
8
0
15
8
8
0
8
22
% D
% Glu:
0
0
8
8
29
43
0
0
0
22
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
36
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
15
0
0
0
8
29
8
0
0
0
0
0
0
% I
% Lys:
15
0
0
8
43
0
15
0
8
0
0
0
8
0
0
% K
% Leu:
0
8
50
43
0
0
43
0
36
8
0
8
15
15
8
% L
% Met:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
22
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
0
29
0
8
0
0
0
8
36
8
0
% Q
% Arg:
50
0
0
0
0
0
8
0
8
0
0
0
8
0
8
% R
% Ser:
8
8
0
0
0
0
0
0
0
0
8
65
8
15
0
% S
% Thr:
0
8
0
0
0
0
0
36
0
0
0
0
8
8
36
% T
% Val:
15
0
8
8
0
0
0
0
0
8
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _