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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFT1
All Species:
25.76
Human Site:
Y453
Identified Species:
43.59
UniProt:
Q96AA3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AA3
NP_443091.1
541
60335
Y453
S
L
C
F
I
H
R
Y
Y
R
R
S
P
H
R
Chimpanzee
Pan troglodytes
XP_516524
541
60171
Y453
S
L
C
F
I
H
C
Y
Y
R
R
S
P
H
R
Rhesus Macaque
Macaca mulatta
XP_001083942
541
60359
Y453
S
L
C
F
I
H
R
Y
Y
R
R
S
P
H
R
Dog
Lupus familis
XP_533793
622
68442
Y534
S
L
C
F
I
H
R
Y
Y
R
K
S
P
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3B8
541
60285
Y453
S
L
S
F
I
H
H
Y
F
R
E
S
P
H
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512002
281
31879
L206
P
H
R
P
L
V
G
L
L
L
S
P
W
L
I
Chicken
Gallus gallus
NP_001136344
539
60350
Y452
S
I
H
Y
I
Y
G
Y
F
K
E
S
S
Y
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688354
540
60871
Y453
S
I
V
Y
I
R
Q
Y
F
L
Q
S
E
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y123
556
62408
Q480
S
T
Y
Y
I
R
H
Q
Y
R
P
L
S
L
D
Honey Bee
Apis mellifera
XP_395946
528
60042
R443
S
I
I
F
I
N
K
R
Y
K
D
T
M
Y
R
Nematode Worm
Caenorhab. elegans
Q23444
522
58137
G442
R
T
I
R
E
Y
L
G
D
K
C
P
S
F
T
Sea Urchin
Strong. purpuratus
XP_791675
1305
146810
F457
S
I
Y
F
I
T
K
F
Y
S
G
S
S
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169121
534
59492
Y452
S
A
V
F
I
K
D
Y
F
K
G
S
F
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38206
574
66192
F493
C
G
V
F
L
N
K
F
H
R
E
L
F
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.2
79.5
N.A.
87.4
N.A.
N.A.
40.4
70.2
N.A.
63.9
N.A.
38.1
36.5
29.3
23.1
Protein Similarity:
100
98.8
98.7
82.6
N.A.
92.4
N.A.
N.A.
43.9
82.4
N.A.
77.4
N.A.
54.3
55.8
50
31.1
P-Site Identity:
100
93.3
100
93.3
N.A.
73.3
N.A.
N.A.
0
33.3
N.A.
40
N.A.
26.6
33.3
0
40
P-Site Similarity:
100
93.3
100
100
N.A.
80
N.A.
N.A.
6.6
73.3
N.A.
73.3
N.A.
33.3
73.3
13.3
60
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
52.8
N.A.
N.A.
48.4
N.A.
P-Site Identity:
N.A.
33.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
29
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
15
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
22
0
8
0
0
% E
% Phe:
0
0
0
65
0
0
0
15
29
0
0
0
15
8
8
% F
% Gly:
0
8
0
0
0
0
15
8
0
0
15
0
0
0
0
% G
% His:
0
8
8
0
0
36
15
0
8
0
0
0
0
43
0
% H
% Ile:
0
29
15
0
79
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
8
22
0
0
29
8
0
0
0
0
% K
% Leu:
0
36
0
0
15
0
8
8
8
15
0
15
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
8
15
36
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
8
0
8
8
0
15
22
8
0
50
22
0
0
0
65
% R
% Ser:
79
0
8
0
0
0
0
0
0
8
8
65
29
8
0
% S
% Thr:
0
15
0
0
0
8
0
0
0
0
0
8
0
8
8
% T
% Val:
0
0
22
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
15
22
0
15
0
58
50
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _