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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISOC2
All Species:
18.98
Human Site:
S7
Identified Species:
37.97
UniProt:
Q96AB3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AB3
NP_001129673.1
205
22337
S7
_
M
A
A
A
R
P
S
L
G
R
V
L
P
G
Chimpanzee
Pan troglodytes
XP_001135720
220
24001
S7
_
M
A
A
A
R
P
S
L
G
R
V
L
P
G
Rhesus Macaque
Macaca mulatta
XP_001088057
205
22323
I7
_
M
A
A
A
R
P
I
L
G
R
V
L
P
G
Dog
Lupus familis
XP_850761
204
22220
N7
_
M
A
T
M
R
S
N
L
G
R
V
L
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P85094
206
22399
S7
_
M
A
A
A
R
A
S
L
G
R
I
L
P
E
Rat
Rattus norvegicus
Q5U3Z3
210
23139
S7
_
M
A
A
A
R
A
S
L
G
R
I
F
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521429
466
49169
S152
G
T
E
M
A
R
S
S
L
G
R
V
L
P
G
Chicken
Gallus gallus
XP_413969
292
31709
T100
P
L
Q
I
Q
M
T
T
L
G
N
L
T
P
S
Frog
Xenopus laevis
Q5PQ71
205
22642
I7
_
M
S
S
L
R
R
I
G
K
L
G
E
R
S
Zebra Danio
Brachydanio rerio
Q08C33
283
31307
T91
P
L
Q
M
D
I
T
T
L
G
N
L
S
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502315
199
21831
I7
_
M
A
A
R
K
L
I
A
R
I
N
P
T
N
Sea Urchin
Strong. purpuratus
XP_795064
195
21855
G7
_
M
A
G
K
N
L
G
K
L
V
L
R
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
95.6
88.7
N.A.
83
73.3
N.A.
30.8
38.3
66.3
37.4
N.A.
N.A.
N.A.
51.7
54.1
Protein Similarity:
100
86.8
97.5
93.6
N.A.
91.2
83.3
N.A.
36.4
49.6
83.4
50.5
N.A.
N.A.
N.A.
68.2
73.6
P-Site Identity:
100
100
92.8
71.4
N.A.
78.5
71.4
N.A.
66.6
20
14.2
20
N.A.
N.A.
N.A.
21.4
14.2
P-Site Similarity:
100
100
92.8
78.5
N.A.
85.7
78.5
N.A.
73.3
40
28.5
40
N.A.
N.A.
N.A.
28.5
21.4
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
50
50
0
17
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
9
0
0
0
9
9
75
0
9
0
0
42
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
0
25
0
0
9
17
0
0
0
% I
% Lys:
0
0
0
0
9
9
0
0
9
9
0
0
0
0
0
% K
% Leu:
0
17
0
0
9
0
17
0
75
9
9
25
50
0
0
% L
% Met:
0
75
0
17
9
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
17
9
0
9
9
% N
% Pro:
17
0
0
0
0
0
25
0
0
0
0
0
9
75
0
% P
% Gln:
0
0
17
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
67
9
0
0
9
59
0
9
9
0
% R
% Ser:
0
0
9
9
0
0
17
42
0
0
0
0
9
0
25
% S
% Thr:
0
9
0
9
0
0
17
17
0
0
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _