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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA2
All Species:
5.15
Human Site:
S106
Identified Species:
9.44
UniProt:
Q96AD5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AD5
NP_065109.1
504
55316
S106
L
K
V
L
P
A
D
S
H
E
H
A
S
G
R
Chimpanzee
Pan troglodytes
XP_525619
429
47940
A103
V
K
Q
Q
L
Q
D
A
L
P
P
D
A
H
V
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
V106
Y
K
Y
L
P
A
N
V
H
Q
L
I
S
G
K
Dog
Lupus familis
XP_854164
454
49903
S106
L
K
T
L
P
A
D
S
H
E
R
A
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ56
486
53638
C106
L
K
T
L
P
A
D
C
H
E
R
A
N
G
R
Rat
Rattus norvegicus
P0C548
478
52548
C106
L
K
T
L
P
A
D
C
H
T
R
A
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
L62
V
H
L
C
Q
I
P
L
D
L
L
C
E
I
L
Chicken
Gallus gallus
NP_001106762
483
53464
G106
S
K
T
V
P
E
N
G
H
E
V
A
A
G
R
Frog
Xenopus laevis
NP_001087449
506
56166
A106
Y
R
N
L
P
E
N
A
H
E
L
A
S
G
K
Zebra Danio
Brachydanio rerio
NP_001002338
473
52215
A106
Y
R
D
L
P
S
N
A
H
T
L
S
S
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
F160
V
R
Y
M
D
G
A
F
S
D
N
L
P
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
A107
E
V
I
L
P
P
N
A
Y
E
M
C
T
G
R
Sea Urchin
Strong. purpuratus
XP_787685
643
72506
T175
D
K
T
C
K
T
I
T
V
S
P
L
S
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
34.7
82.1
N.A.
84.3
84.1
N.A.
36.1
65.8
50
48.2
N.A.
32.7
N.A.
30.2
30.4
Protein Similarity:
100
46.8
51.5
84.5
N.A.
88.2
87.9
N.A.
50.2
75.7
65
62.9
N.A.
49
N.A.
47.5
46.3
P-Site Identity:
100
13.3
46.6
86.6
N.A.
73.3
73.3
N.A.
0
46.6
46.6
40
N.A.
0
N.A.
33.3
20
P-Site Similarity:
100
33.3
66.6
86.6
N.A.
80
73.3
N.A.
13.3
66.6
73.3
73.3
N.A.
33.3
N.A.
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
39
8
31
0
0
0
47
16
0
0
% A
% Cys:
0
0
0
16
0
0
0
16
0
0
0
16
0
0
0
% C
% Asp:
8
0
8
0
8
0
39
0
8
8
0
8
0
0
0
% D
% Glu:
8
0
0
0
0
16
0
0
0
47
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
0
0
77
0
% G
% His:
0
8
0
0
0
0
0
0
62
0
8
0
0
8
0
% H
% Ile:
0
0
8
0
0
8
8
0
0
0
0
8
0
16
0
% I
% Lys:
0
62
0
0
8
0
0
0
0
0
0
0
0
0
16
% K
% Leu:
31
0
8
62
8
0
0
8
8
8
31
16
0
0
16
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
39
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
70
8
8
0
0
8
16
0
8
0
0
% P
% Gln:
0
0
8
8
8
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
0
0
0
0
0
24
0
0
0
54
% R
% Ser:
8
0
0
0
0
8
0
16
8
8
0
8
54
0
0
% S
% Thr:
0
0
39
0
0
8
0
8
0
16
0
0
8
0
0
% T
% Val:
24
8
8
8
0
0
0
8
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
16
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _