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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA2
All Species:
5.15
Human Site:
S288
Identified Species:
9.44
UniProt:
Q96AD5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AD5
NP_065109.1
504
55316
S288
S
A
Q
A
E
D
Y
S
Q
L
P
G
E
D
H
Chimpanzee
Pan troglodytes
XP_525619
429
47940
T257
F
L
E
R
R
G
L
T
K
E
P
V
L
W
T
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
S271
S
S
S
E
G
M
D
S
E
V
T
A
P
G
W
Dog
Lupus familis
XP_854164
454
49903
L265
S
G
H
P
Q
P
A
L
E
D
H
I
L
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ56
486
53638
R294
E
D
Q
L
Q
P
Y
R
K
D
R
I
L
E
H
Rat
Rattus norvegicus
P0C548
478
52548
T284
A
A
V
T
E
E
R
T
G
G
E
D
R
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
L216
H
L
N
Y
H
V
S
L
G
N
A
Y
L
T
S
Chicken
Gallus gallus
NP_001106762
483
53464
A292
D
Q
M
E
D
N
T
A
L
A
V
V
E
D
H
Frog
Xenopus laevis
NP_001087449
506
56166
T304
R
K
V
L
E
G
Q
T
P
W
S
L
D
K
R
Zebra Danio
Brachydanio rerio
NP_001002338
473
52215
M264
A
A
C
P
G
V
D
M
A
L
I
Q
A
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001163445
553
62224
L331
A
T
V
P
M
D
F
L
L
A
T
I
S
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
F310
S
A
N
A
L
N
S
F
R
T
R
G
E
S
E
Sea Urchin
Strong. purpuratus
XP_787685
643
72506
Q391
S
L
P
P
E
V
I
Q
V
L
H
S
A
C
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
34.7
82.1
N.A.
84.3
84.1
N.A.
36.1
65.8
50
48.2
N.A.
32.7
N.A.
30.2
30.4
Protein Similarity:
100
46.8
51.5
84.5
N.A.
88.2
87.9
N.A.
50.2
75.7
65
62.9
N.A.
49
N.A.
47.5
46.3
P-Site Identity:
100
6.6
13.3
13.3
N.A.
20
13.3
N.A.
0
20
6.6
13.3
N.A.
6.6
N.A.
33.3
26.6
P-Site Similarity:
100
26.6
33.3
33.3
N.A.
40
33.3
N.A.
0
40
20
20
N.A.
20
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
31
0
16
0
0
8
8
8
16
8
8
16
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
0
0
8
16
16
0
0
16
0
8
8
16
0
% D
% Glu:
8
0
8
16
31
8
0
0
16
8
8
0
24
16
8
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
16
16
0
0
16
8
0
16
0
8
0
% G
% His:
8
0
8
0
8
0
0
0
0
0
16
0
0
0
39
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
24
0
8
8
% I
% Lys:
0
8
0
0
0
0
0
0
16
0
0
0
0
16
0
% K
% Leu:
0
24
0
16
8
0
8
24
16
24
0
8
31
0
8
% L
% Met:
0
0
8
0
8
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
16
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
31
0
16
0
0
8
0
16
0
8
0
8
% P
% Gln:
0
8
16
0
16
0
8
8
8
0
0
8
0
0
0
% Q
% Arg:
8
0
0
8
8
0
8
8
8
0
16
0
8
0
8
% R
% Ser:
39
8
8
0
0
0
16
16
0
0
8
8
8
8
8
% S
% Thr:
0
8
0
8
0
0
8
24
0
8
16
0
0
16
8
% T
% Val:
0
0
24
0
0
24
0
0
8
8
8
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% W
% Tyr:
0
0
0
8
0
0
16
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _