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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A46
All Species:
31.52
Human Site:
S227
Identified Species:
63.03
UniProt:
Q96AG3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AG3
NP_620128.1
418
46174
S227
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100405
418
46123
S227
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
T
Dog
Lupus familis
XP_545993
573
63132
S382
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS4
418
46206
S227
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
T
Rat
Rattus norvegicus
Q5EB62
418
46192
S227
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513186
467
51556
S276
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
P
Chicken
Gallus gallus
Q5ZIG3
408
44623
S217
S
L
I
E
T
V
Q
S
E
I
I
R
D
N
P
Frog
Xenopus laevis
Q6INQ6
417
46131
S226
S
L
I
E
T
V
Q
S
E
I
I
H
D
N
P
Zebra Danio
Brachydanio rerio
Q6DGU5
405
44891
P218
S
E
I
I
R
D
N
P
G
I
L
D
C
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573096
421
47337
A221
G
R
M
L
P
A
W
A
L
I
G
P
S
V
S
Honey Bee
Apis mellifera
XP_394616
397
44206
V212
G
A
I
R
L
V
E
V
S
N
K
G
R
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P0C582
331
35028
S147
V
G
F
K
E
R
A
S
A
G
L
A
A
G
G
Conservation
Percent
Protein Identity:
100
N.A.
99.2
61.2
N.A.
89
89
N.A.
67
79.1
72.2
71
N.A.
36.3
36.5
N.A.
N.A.
Protein Similarity:
100
N.A.
99.7
65.6
N.A.
93.5
93.7
N.A.
73.6
87.5
83.4
82.7
N.A.
56.5
55.5
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
20
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
26.6
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
9
9
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
9
67
0
0
% D
% Glu:
0
9
0
67
9
0
9
0
67
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
9
0
0
0
0
0
0
9
9
9
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
84
9
0
0
0
0
0
84
67
0
0
0
9
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% K
% Leu:
0
67
0
9
9
0
0
0
9
0
17
0
0
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
0
0
0
67
0
% N
% Pro:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
25
% P
% Gln:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
9
9
0
0
0
0
0
59
9
0
0
% R
% Ser:
75
0
0
0
0
0
0
75
9
0
0
0
9
0
9
% S
% Thr:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
42
% T
% Val:
9
0
0
0
0
75
0
9
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _