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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A46 All Species: 20.3
Human Site: T294 Identified Species: 40.61
UniProt: Q96AG3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AG3 NP_620128.1 418 46174 T294 L L I L K R K T Y N S H L A E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100405 418 46123 T294 L L I L K R K T Y N S H L A E
Dog Lupus familis XP_545993 573 63132 T449 L L I L K R K T Y S S H L A E
Cat Felis silvestris
Mouse Mus musculus Q9CQS4 418 46206 T294 L L I L K R K T Y N S H L A E
Rat Rattus norvegicus Q5EB62 418 46192 T294 L L I L K R K T C S S H L A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513186 467 51556 Q343 L L I L K R K Q V Q S Q A T E
Chicken Gallus gallus Q5ZIG3 408 44623 N284 L L F L K R E N S H S L P T E
Frog Xenopus laevis Q6INQ6 417 46131 S293 L F F I K K K S P P R L P A D
Zebra Danio Brachydanio rerio Q6DGU5 405 44891 P282 R R R N N G S P K H S S P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573096 421 47337 L296 F F P F E T I L H R L Q L Q G
Honey Bee Apis mellifera XP_394616 397 44206 V273 R D L L S E T V A Q D I E L Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P0C582 331 35028 A208 A A L W A G A A P T V V R A M
Conservation
Percent
Protein Identity: 100 N.A. 99.2 61.2 N.A. 89 89 N.A. 67 79.1 72.2 71 N.A. 36.3 36.5 N.A. N.A.
Protein Similarity: 100 N.A. 99.7 65.6 N.A. 93.5 93.7 N.A. 73.6 87.5 83.4 82.7 N.A. 56.5 55.5 N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 86.6 N.A. 60 46.6 26.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 60 60 53.3 13.3 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 33.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 9 9 9 0 0 0 9 59 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 9 % D
% Glu: 0 0 0 0 9 9 9 0 0 0 0 0 9 0 59 % E
% Phe: 9 17 17 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 0 0 0 0 0 0 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 9 17 0 42 0 0 0 % H
% Ile: 0 0 50 9 0 0 9 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 67 9 59 0 9 0 0 0 0 0 0 % K
% Leu: 67 59 17 67 0 0 0 9 0 0 9 17 50 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 9 9 0 0 9 0 25 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 9 17 9 0 0 25 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 17 0 17 0 9 9 % Q
% Arg: 17 9 9 0 0 59 0 0 0 9 9 0 9 0 0 % R
% Ser: 0 0 0 0 9 0 9 9 9 17 67 9 0 0 9 % S
% Thr: 0 0 0 0 0 9 9 42 0 9 0 0 0 17 0 % T
% Val: 0 0 0 0 0 0 0 9 9 0 9 9 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _