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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC59
All Species:
11.21
Human Site:
S244
Identified Species:
24.67
UniProt:
Q96AG4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AG4
NP_060979.2
307
34930
S244
P
P
R
K
H
T
R
S
W
A
V
L
K
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093756
240
27274
R173
E
R
E
A
E
K
K
R
E
A
K
Q
R
A
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q8
307
34859
S244
P
P
R
K
H
T
R
S
W
A
V
L
K
V
L
Rat
Rattus norvegicus
Q5RJR8
307
34851
S244
P
P
R
K
H
N
R
S
W
A
V
L
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510940
305
34466
P242
P
P
P
R
P
S
W
P
W
A
L
L
K
V
L
Chicken
Gallus gallus
Q5F334
339
38647
S277
A
R
H
K
H
S
W
S
R
S
V
L
R
A
L
Frog
Xenopus laevis
Q8AVS8
307
35413
R241
K
E
K
K
L
A
Q
R
Q
S
R
L
R
K
I
Zebra Danio
Brachydanio rerio
Q6NWG1
314
35886
A241
A
P
E
S
V
P
K
A
K
R
S
I
C
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121810
270
31077
Q204
G
F
K
E
N
V
Y
Q
F
F
M
S
M
I
L
Nematode Worm
Caenorhab. elegans
NP_499730
444
49391
N204
K
Q
Q
R
E
T
V
N
A
A
S
H
K
N
N
Sea Urchin
Strong. purpuratus
XP_793338
179
20031
G131
P
T
L
N
K
I
V
G
D
C
L
D
D
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
75.5
N.A.
N.A.
95.4
94.4
N.A.
74.9
65.1
57.6
55.4
N.A.
N.A.
32.2
27.7
33.2
Protein Similarity:
100
N.A.
76.5
N.A.
N.A.
97.7
96.4
N.A.
86.6
76.4
75.5
73.2
N.A.
N.A.
48.8
43.9
44.6
P-Site Identity:
100
N.A.
6.6
N.A.
N.A.
93.3
86.6
N.A.
46.6
40
13.3
13.3
N.A.
N.A.
6.6
20
6.6
P-Site Similarity:
100
N.A.
20
N.A.
N.A.
100
86.6
N.A.
73.3
60
46.6
33.3
N.A.
N.A.
46.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
0
10
0
10
10
55
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% D
% Glu:
10
10
19
10
19
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
37
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
10
% I
% Lys:
19
0
19
46
10
10
19
0
10
0
10
0
46
19
10
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
19
55
0
10
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
10
10
10
0
10
0
0
0
0
0
10
10
% N
% Pro:
46
46
10
0
10
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
10
10
10
0
0
10
0
0
10
% Q
% Arg:
0
19
28
19
0
0
28
19
10
10
10
0
28
0
0
% R
% Ser:
0
0
0
10
0
19
0
37
0
19
19
10
0
10
0
% S
% Thr:
0
10
0
0
0
28
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
10
19
0
0
0
37
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
19
0
37
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _