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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VTI1A All Species: 23.03
Human Site: S129 Identified Species: 38.97
UniProt: Q96AJ9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AJ9 NP_660207.2 203 23435 S129 T E R L E R S S R R L E A G Y
Chimpanzee Pan troglodytes XP_001146992 225 26196 S129 T E R L E R S S R R L E A G Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O89116 217 24968 S129 T E R L E R S S R R L E A G Y
Rat Rattus norvegicus Q9JI51 224 26024 T129 R A H L L D N T E R L E R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513273 244 28059 S156 T E R L E R S S R R L E A G Y
Chicken Gallus gallus XP_001233060 217 25018 S129 T E R L E R S S R R L E A G Y
Frog Xenopus laevis NP_001084318 194 22557 L104 D E V R N E L L G D D G N S S
Zebra Danio Brachydanio rerio NP_001030152 191 22073 L104 D E V R N E L L G D D G S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_612053 230 25870 G135 S E R I E R T G N R L T E G Y
Honey Bee Apis mellifera XP_623763 234 27093 G130 S E R I D R T G R T L Q N G Y
Nematode Worm Caenorhab. elegans P83351 277 31097 L199 M S A N L R N L Q R L G A D L
Sea Urchin Strong. purpuratus XP_796642 170 19589 D98 S K V S S R D D G A R E E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEL6 221 24932 T134 T E R L G R T T D R V K D S R
Baker's Yeast Sacchar. cerevisiae Q04338 217 24650 G131 H A I L Q K S G D R L K D A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 N.A. N.A. N.A. 85.2 81.6 N.A. 65.1 81.5 79.8 73.8 N.A. 39.1 35.4 21.2 39.4
Protein Similarity: 100 86.2 N.A. N.A. N.A. 88 85.2 N.A. 71.7 86.1 87.1 83.2 N.A. 58.7 57.6 37.1 62
P-Site Identity: 100 100 N.A. N.A. N.A. 100 26.6 N.A. 100 100 6.6 6.6 N.A. 53.3 46.6 26.6 13.3
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 40 N.A. 100 100 6.6 13.3 N.A. 73.3 80 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 50.6 N.A.
P-Site Identity: N.A. N.A. N.A. 40 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 0 0 0 0 8 0 0 43 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 8 8 8 8 15 15 15 0 15 8 0 % D
% Glu: 0 72 0 0 43 15 0 0 8 0 0 50 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 22 22 0 0 22 0 50 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 8 0 0 0 0 0 15 0 0 0 % K
% Leu: 0 0 0 58 15 0 15 22 0 0 72 0 0 8 15 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 15 0 15 0 8 0 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 8 0 58 15 0 72 0 0 43 72 8 0 8 0 8 % R
% Ser: 22 8 0 8 8 0 43 36 0 0 0 0 8 29 29 % S
% Thr: 43 0 0 0 0 0 22 15 0 8 0 8 0 0 0 % T
% Val: 0 0 22 0 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _