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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACD All Species: 1.52
Human Site: S379 Identified Species: 8.33
UniProt: Q96AP0 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AP0 NP_001075955.1 544 57758 S379 S S E E S G T S I S L L P A L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092455 455 48807 R309 A A P D P G Q R S S S Q P P P
Dog Lupus familis XP_853906 453 48214 G307 A S D L V Q K G S S Q A V P A
Cat Felis silvestris
Mouse Mus musculus Q5EE38 416 44695 T271 S L L S A L A T S D P G Q M D
Rat Rattus norvegicus Q4FZR5 417 45573 S272 L L S A L P T S D P G Q K D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 79.5 64.3 N.A. 50.5 51.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 81 70.4 N.A. 59.7 60.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 20 13.3 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 40 26.6 N.A. 20 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 20 0 20 20 0 20 0 0 0 0 20 0 20 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 20 0 0 0 0 20 20 0 0 0 20 20 % D
% Glu: 0 0 20 20 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 40 0 20 0 0 20 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 20 0 0 0 0 0 20 0 0 % K
% Leu: 20 40 20 20 20 20 0 0 0 0 20 20 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 0 0 20 0 20 20 0 0 0 20 20 0 40 40 20 % P
% Gln: 0 0 0 0 0 20 20 0 0 0 20 40 20 0 0 % Q
% Arg: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % R
% Ser: 40 40 20 20 20 0 0 40 60 60 20 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 40 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 20 0 0 0 0 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _