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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESAM
All Species:
18.48
Human Site:
S359
Identified Species:
45.19
UniProt:
Q96AP7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AP7
NP_620411.2
390
41176
S359
G
A
H
P
Q
P
I
S
P
I
P
G
G
V
S
Chimpanzee
Pan troglodytes
XP_508839
390
41177
S359
G
A
H
P
Q
P
I
S
P
I
P
G
G
V
S
Rhesus Macaque
Macaca mulatta
XP_001110293
390
40928
S359
G
A
N
P
Q
P
I
S
L
I
P
G
G
V
S
Dog
Lupus familis
XP_546427
393
41165
S362
G
A
Q
P
Q
P
I
S
P
S
P
G
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q925F2
394
41792
S363
E
P
P
P
Q
A
V
S
L
T
P
G
G
V
S
Rat
Rattus norvegicus
Q6AYD4
394
41918
S363
G
P
P
P
Q
A
V
S
L
T
P
G
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516661
254
26970
G224
M
V
T
G
A
V
V
G
T
A
I
G
L
G
L
Chicken
Gallus gallus
Q9PWR4
335
36491
Q305
P
S
N
A
T
N
E
Q
P
S
A
D
E
A
A
Frog
Xenopus laevis
Q91664
318
34411
E288
E
A
N
E
P
P
K
E
N
L
G
A
S
E
P
Zebra Danio
Brachydanio rerio
Q90Y50
372
40645
I341
R
P
P
S
H
A
P
I
P
P
P
S
R
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.4
78.8
N.A.
72.3
71.5
N.A.
36.4
24.1
23.5
27.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.9
86
N.A.
80.7
80.4
N.A.
46.9
42
40.7
47.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
53.3
60
N.A.
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
60
66.6
N.A.
13.3
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
10
10
30
0
0
0
10
10
10
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
20
0
0
10
0
0
10
10
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
10
0
0
0
10
0
0
10
70
60
10
0
% G
% His:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
40
10
0
30
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
30
10
0
0
10
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
30
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
30
30
60
10
50
10
0
50
10
70
0
0
0
10
% P
% Gln:
0
0
10
0
60
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
0
10
0
0
0
60
0
20
0
10
10
0
60
% S
% Thr:
0
0
10
0
10
0
0
0
10
20
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
30
0
0
0
0
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _