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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS33A All Species: 35.45
Human Site: T465 Identified Species: 52
UniProt: Q96AX1 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AX1 NP_075067.2 596 67611 T465 G G R N N Y P T I R K T L R L
Chimpanzee Pan troglodytes XP_001167547 566 64240 T435 G G R N N Y P T I R K T L R L
Rhesus Macaque Macaca mulatta XP_001098488 534 60475 M412 R K T L R L W M D D V N E Q N
Dog Lupus familis XP_534660 596 67606 T465 G G R N N Y P T I R K T L R L
Cat Felis silvestris
Mouse Mus musculus Q9D2N9 598 67522 T467 G G R N N Y P T I R K T L R L
Rat Rattus norvegicus Q63615 597 67495 T466 G G R N N Y P T I R K T L R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506548 578 65937 T447 G G R N N Y P T I R K T M R L
Chicken Gallus gallus XP_415153 601 68528 T466 G G R N N Y P T I R K T L R L
Frog Xenopus laevis NP_001121352 601 68172 T466 S S R N N Y P T I R K T L R L
Zebra Danio Brachydanio rerio NP_001093443 599 68084 T464 T M R N N Y P T I R K T L K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y1I2 617 68748 L479 E S R A Y S V L R K T L H L T
Honey Bee Apis mellifera XP_395353 609 68702 L468 S T R K Y T V L R K A L R L T
Nematode Worm Caenorhab. elegans P34260 603 68147 K463 Y G S S A L N K V L K M Q K M
Sea Urchin Strong. purpuratus XP_798265 622 70760 R483 Q K T Y P T I R K T L K L V M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94KJ7 592 66894 V453 F K S N W L T V K R T L K L I
Baker's Yeast Sacchar. cerevisiae P20795 691 79253 T495 F T S K T G K T D L H I T T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 89.5 98.3 N.A. 97.3 96.8 N.A. 90.5 91 85.6 83.9 N.A. 44.4 52.5 27.6 63.3
Protein Similarity: 100 94.8 89.5 99.6 N.A. 98.8 98.9 N.A. 94.3 94.6 91.6 91.4 N.A. 61.9 71.2 49 79.4
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 93.3 100 86.6 80 N.A. 6.6 6.6 13.3 6.6
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 86.6 86.6 N.A. 13.3 13.3 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. 38 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. 60.5 40.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 13 7 0 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 44 50 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 57 0 0 7 0 0 7 % I
% Lys: 0 19 0 13 0 0 7 7 13 13 63 7 7 13 0 % K
% Leu: 0 0 0 7 0 19 0 13 0 13 7 19 57 19 57 % L
% Met: 0 7 0 0 0 0 0 7 0 0 0 7 7 0 13 % M
% Asn: 0 0 0 63 57 0 7 0 0 0 0 7 0 0 7 % N
% Pro: 0 0 0 0 7 0 57 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % Q
% Arg: 7 0 69 0 7 0 0 7 13 63 0 0 7 50 0 % R
% Ser: 13 13 19 7 0 7 0 0 0 0 0 0 0 0 7 % S
% Thr: 7 13 13 0 7 13 7 63 0 7 13 57 7 7 13 % T
% Val: 0 0 0 0 0 0 13 7 7 0 7 0 0 7 0 % V
% Trp: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 13 57 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _