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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIB2 All Species: 18.48
Human Site: S472 Identified Species: 36.97
UniProt: Q96AX9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AX9 NP_543151.1 1013 109939 S472 E R A R E N K S S L S V A L D
Chimpanzee Pan troglodytes XP_001155032 967 103188 S396 E R A R E N K S S L S V A L D
Rhesus Macaque Macaca mulatta XP_001096926 1107 119497 S566 E R A R E N K S S L S V A L D
Dog Lupus familis XP_536706 957 103786 S414 E R A R E N K S F L S V A L E
Cat Felis silvestris
Mouse Mus musculus Q8R516 973 105942 G422 A A S V S V A G S L S V A L D
Rat Rattus norvegicus Q68LP1 971 105524 G422 A A S V P V A G S L S V A L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIJ9 954 106321 S414 E N A K E S K S T L I T V L E
Frog Xenopus laevis Q6GNY1 1011 110670 E427 K K L F E T Q E S G D L N E E
Zebra Danio Brachydanio rerio Q804S5 1030 112669 E427 K K L F E T Q E S G D I N E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUX2 1226 129854 S506 I P S S E R L S A I L K K L F
Honey Bee Apis mellifera XP_392821 969 106504 D453 E V E K L L R D A A R G E A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780333 1026 112002 G393 D R A E E L Q G N L H E L L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.8 89.6 88.1 N.A. 87.7 87.2 N.A. N.A. 65.2 39.2 38.6 N.A. 32.8 39.6 N.A. 40.5
Protein Similarity: 100 72 90.2 90.5 N.A. 90.1 89.8 N.A. N.A. 78.9 56.3 55.5 N.A. 46.4 55.5 N.A. 58.2
P-Site Identity: 100 100 100 86.6 N.A. 46.6 46.6 N.A. N.A. 46.6 13.3 13.3 N.A. 20 6.6 N.A. 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 53.3 53.3 N.A. N.A. 73.3 46.6 46.6 N.A. 40 26.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 50 0 0 0 17 0 17 9 0 0 50 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 0 0 17 0 0 0 42 % D
% Glu: 50 0 9 9 75 0 0 17 0 0 0 9 9 17 34 % E
% Phe: 0 0 0 17 0 0 0 0 9 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 0 25 0 17 0 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 9 9 9 0 0 0 % I
% Lys: 17 17 0 17 0 0 42 0 0 0 0 9 9 0 0 % K
% Leu: 0 0 17 0 9 17 9 0 0 67 9 9 9 75 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 34 0 0 9 0 0 0 17 0 0 % N
% Pro: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 9 % Q
% Arg: 0 42 0 34 0 9 9 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 25 9 9 9 0 50 59 0 50 0 0 0 0 % S
% Thr: 0 0 0 0 0 17 0 0 9 0 0 9 0 0 0 % T
% Val: 0 9 0 17 0 17 0 0 0 0 0 50 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _