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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIB2 All Species: 19.39
Human Site: S475 Identified Species: 38.79
UniProt: Q96AX9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AX9 NP_543151.1 1013 109939 S475 R E N K S S L S V A L D K L R
Chimpanzee Pan troglodytes XP_001155032 967 103188 S399 R E N K S S L S V A L D K L R
Rhesus Macaque Macaca mulatta XP_001096926 1107 119497 S569 R E N K S S L S V A L D K L R
Dog Lupus familis XP_536706 957 103786 S417 R E N K S F L S V A L E K L R
Cat Felis silvestris
Mouse Mus musculus Q8R516 973 105942 S425 V S V A G S L S V A L D K L R
Rat Rattus norvegicus Q68LP1 971 105524 S425 V P V A G S L S V A L D K L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIJ9 954 106321 I417 K E S K S T L I T V L E K L L
Frog Xenopus laevis Q6GNY1 1011 110670 D430 F E T Q E S G D L N E E L V K
Zebra Danio Brachydanio rerio Q804S5 1030 112669 D430 F E T Q E S G D I N E E L V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUX2 1226 129854 L509 S E R L S A I L K K L F E P N
Honey Bee Apis mellifera XP_392821 969 106504 R456 K L L R D A A R G E A G V S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780333 1026 112002 H396 E E L Q G N L H E L L Q E I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.8 89.6 88.1 N.A. 87.7 87.2 N.A. N.A. 65.2 39.2 38.6 N.A. 32.8 39.6 N.A. 40.5
Protein Similarity: 100 72 90.2 90.5 N.A. 90.1 89.8 N.A. N.A. 78.9 56.3 55.5 N.A. 46.4 55.5 N.A. 58.2
P-Site Identity: 100 100 100 86.6 N.A. 66.6 66.6 N.A. N.A. 46.6 13.3 13.3 N.A. 20 0 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 66.6 N.A. N.A. 73.3 46.6 46.6 N.A. 40 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 17 9 0 0 50 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 17 0 0 0 42 0 0 0 % D
% Glu: 9 75 0 0 17 0 0 0 9 9 17 34 17 0 0 % E
% Phe: 17 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 25 0 17 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 9 9 0 0 0 0 9 0 % I
% Lys: 17 0 0 42 0 0 0 0 9 9 0 0 59 0 17 % K
% Leu: 0 9 17 9 0 0 67 9 9 9 75 0 17 59 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 34 0 0 9 0 0 0 17 0 0 0 0 9 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 25 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 34 0 9 9 0 0 0 9 0 0 0 0 0 0 50 % R
% Ser: 9 9 9 0 50 59 0 50 0 0 0 0 0 9 0 % S
% Thr: 0 0 17 0 0 9 0 0 9 0 0 0 0 0 0 % T
% Val: 17 0 17 0 0 0 0 0 50 9 0 0 9 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _