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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM119B All Species: 6.36
Human Site: S180 Identified Species: 11.67
UniProt: Q96AZ1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AZ1 NP_056248.2 226 24911 S180 H G T I Y L A S K M R K E H G
Chimpanzee Pan troglodytes XP_001167315 226 24844 S180 H G T I N L A S K M R K E H G
Rhesus Macaque Macaca mulatta XP_001099061 227 25422 C182 H S V I L L A C R I R Y E R D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CQL0 218 24267 C173 N S V I L L A C R I R Y E R D
Rat Rattus norvegicus Q4KM84 362 39990 S313 N G R V L L A S K A H Y F G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516290 242 25748 A195 R G T A L L A A K M R E E H G
Chicken Gallus gallus XP_421949 216 24436 C171 Q T V I L L S C R I R Y E R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5BLD8 218 24426 C173 D T V V L L S C R I R Y E R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30643 371 42049 A301 H S K A A I V A C T R R N E S
Sea Urchin Strong. purpuratus XP_781765 199 22589 R166 S C R I R Y E R D N N F L D M
Poplar Tree Populus trichocarpa XP_002331909 260 28315 G214 Q T T I F L A G E L R N D A V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177475 316 34357 G255 Q T T I F L S G E L R N D A V
Baker's Yeast Sacchar. cerevisiae P53970 246 27720 M199 I N P P V I L M A Y K K R R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 43.6 N.A. N.A. 42 22.1 N.A. 59.9 41.1 N.A. 43.8 N.A. N.A. N.A. 21 34
Protein Similarity: 100 99.5 59.9 N.A. N.A. 60.1 33.7 N.A. 71.4 56.1 N.A. 60.6 N.A. N.A. N.A. 33.9 50.4
P-Site Identity: 100 93.3 40 N.A. N.A. 33.3 33.3 N.A. 66.6 26.6 N.A. 20 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 93.3 53.3 N.A. N.A. 53.3 46.6 N.A. 80 46.6 N.A. 46.6 N.A. N.A. N.A. 33.3 6.6
Percent
Protein Identity: 32.3 N.A. N.A. 27.5 26 N.A.
Protein Similarity: 47.6 N.A. N.A. 41.1 43 N.A.
P-Site Identity: 33.3 N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: 60 N.A. N.A. 60 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 8 0 54 16 8 8 0 0 0 16 0 % A
% Cys: 0 8 0 0 0 0 0 31 8 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 8 0 0 0 16 8 31 % D
% Glu: 0 0 0 0 0 0 8 0 16 0 0 8 54 8 0 % E
% Phe: 0 0 0 0 16 0 0 0 0 0 0 8 8 0 0 % F
% Gly: 0 31 0 0 0 0 0 16 0 0 0 0 0 8 24 % G
% His: 31 0 0 0 0 0 0 0 0 0 8 0 0 24 0 % H
% Ile: 8 0 0 62 0 16 0 0 0 31 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 31 0 8 24 0 0 8 % K
% Leu: 0 0 0 0 47 77 8 0 0 16 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 24 0 0 0 0 8 % M
% Asn: 16 8 0 0 8 0 0 0 0 8 8 16 8 0 0 % N
% Pro: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 16 0 8 0 0 8 31 0 77 8 8 39 0 % R
% Ser: 8 24 0 0 0 0 24 24 0 0 0 0 0 0 8 % S
% Thr: 0 31 39 0 0 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 0 31 16 8 0 8 0 0 0 0 0 0 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 8 0 39 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _