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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ISG20 All Species: 7.58
Human Site: S134 Identified Species: 27.78
UniProt: Q96AZ6 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96AZ6 NP_002192.2 181 20363 S134 R V S L R V L S E R L L H K S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090125 181 20409 S134 R V S L R V L S E R L L H K S
Dog Lupus familis XP_545847 171 19383 N124 W R E A N L Q N C R R V S L R
Cat Felis silvestris
Mouse Mus musculus Q9JL16 300 32484 C134 R V S L R L L C K R L L H K N
Rat Rattus norvegicus B2GUW6 332 37042 A233 R V S L K D L A L N L L H K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521618 281 30503 V235 C R R V S L K V L T L K I L K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664971 321 36705 T264 C V S L K K L T Q A I L K R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.7 75.6 N.A. 47 32.8 N.A. 45.5 N.A. N.A. 27.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 98.9 85 N.A. 52.3 38.8 N.A. 51.5 N.A. N.A. 39.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 6.6 N.A. 73.3 60 N.A. 6.6 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 26.6 N.A. 93.3 73.3 N.A. 20 N.A. N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 0 0 15 0 15 0 0 0 0 0 % A
% Cys: 29 0 0 0 0 0 0 15 15 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 15 % D
% Glu: 0 0 15 0 0 0 0 0 29 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % I
% Lys: 0 0 0 0 29 15 15 0 15 0 0 15 15 58 29 % K
% Leu: 0 0 0 72 0 43 72 0 29 0 72 72 0 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 15 0 15 0 0 0 0 15 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 15 0 15 0 0 0 0 0 0 % Q
% Arg: 58 29 15 0 43 0 0 0 0 58 15 0 0 15 15 % R
% Ser: 0 0 72 0 15 0 0 29 0 0 0 0 15 0 29 % S
% Thr: 0 0 0 0 0 0 0 15 0 15 0 0 0 0 0 % T
% Val: 0 72 0 15 0 29 0 15 0 0 0 15 0 0 0 % V
% Trp: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _