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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45B
All Species:
17.83
Human Site:
S270
Identified Species:
39.23
UniProt:
Q96B21
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B21
NP_620143.1
275
31826
S270
T
Y
Q
T
A
L
L
S
G
S
D
E
E
_
_
Chimpanzee
Pan troglodytes
XP_001151660
275
31822
S270
T
Y
Q
T
A
L
L
S
G
S
D
E
E
_
_
Rhesus Macaque
Macaca mulatta
XP_001111835
573
63247
S568
T
Y
Q
T
A
L
L
S
G
S
D
E
E
_
_
Dog
Lupus familis
XP_536531
532
59743
G527
T
Y
Q
T
S
L
L
G
G
S
D
E
E
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ2
278
32370
S273
T
Y
Q
S
A
L
L
S
G
S
D
E
E
_
_
Rat
Rattus norvegicus
Q497B2
278
32319
S273
T
Y
Q
S
T
L
L
S
G
S
D
E
E
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506350
563
61793
Q458
N
V
H
M
A
L
L
Q
D
L
E
E
E
A
P
Chicken
Gallus gallus
XP_417866
281
32113
N276
G
S
Q
A
A
F
L
N
G
S
D
E
E
_
_
Frog
Xenopus laevis
Q6NS09
280
31983
A275
E
V
E
A
S
L
L
A
G
S
D
E
E
_
_
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
Q278
S
S
Q
K
A
L
L
Q
E
S
D
E
E
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
45.7
42.8
N.A.
79.1
76.9
N.A.
32.1
58.3
62.8
53.7
N.A.
N.A.
N.A.
N.A.
33.8
Protein Similarity:
100
100
46.9
47.3
N.A.
88.4
85.9
N.A.
39.9
75
77.1
71.3
N.A.
N.A.
N.A.
N.A.
55.2
P-Site Identity:
100
100
100
84.6
N.A.
92.3
84.6
N.A.
33.3
61.5
53.8
61.5
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
92.3
N.A.
100
92.3
N.A.
40
69.2
76.9
69.2
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
64
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
82
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
10
0
10
91
91
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
73
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
82
91
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
73
0
0
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
19
0
19
19
0
0
46
0
82
0
0
0
0
0
% S
% Thr:
55
0
0
37
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
82
82
% _