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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM45B All Species: 9.09
Human Site: T33 Identified Species: 20
UniProt: Q96B21 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96B21 NP_620143.1 275 31826 T33 P L K Y F S H T R K N S P L H
Chimpanzee Pan troglodytes XP_001151660 275 31822 T33 P L K Y F S H T R K N S P L H
Rhesus Macaque Macaca mulatta XP_001111835 573 63247 T331 P L K Y F S H T R K N S P L H
Dog Lupus familis XP_536531 532 59743 K290 P L I Y F R Q K G K S S Q L T
Cat Felis silvestris
Mouse Mus musculus Q8VCZ2 278 32370 K33 P L K Y F H H K G L K N N R L
Rat Rattus norvegicus Q497B2 278 32319 K33 P L K Y F H Q K G L K K N R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506350 563 61793 G219 P F K H L T Q G A R S R F S R
Chicken Gallus gallus XP_417866 281 32113 K33 P L R Y L S Q K A S K K S Q K
Frog Xenopus laevis Q6NS09 280 31983 K33 P L R Y L N S K V K G N C R S
Zebra Danio Brachydanio rerio Q6P0S3 283 32742 R33 P F R Q I L R R K E R Q V G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783137 274 30760 D33 A Y S I V V L D N G R Q R P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 45.7 42.8 N.A. 79.1 76.9 N.A. 32.1 58.3 62.8 53.7 N.A. N.A. N.A. N.A. 33.8
Protein Similarity: 100 100 46.9 47.3 N.A. 88.4 85.9 N.A. 39.9 75 77.1 71.3 N.A. N.A. N.A. N.A. 55.2
P-Site Identity: 100 100 100 46.6 N.A. 40 33.3 N.A. 13.3 26.6 26.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 53.3 N.A. 46.6 33.3 N.A. 40 33.3 46.6 26.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 19 0 0 55 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 28 10 10 0 0 10 0 % G
% His: 0 0 0 10 0 19 37 0 0 0 0 0 0 0 28 % H
% Ile: 0 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 55 0 0 0 0 46 10 46 28 19 0 0 10 % K
% Leu: 0 73 0 0 28 10 10 0 0 19 0 0 0 37 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 28 19 19 0 0 % N
% Pro: 91 0 0 0 0 0 0 0 0 0 0 0 28 10 0 % P
% Gln: 0 0 0 10 0 0 37 0 0 0 0 19 10 10 0 % Q
% Arg: 0 0 28 0 0 10 10 10 28 10 19 10 10 28 19 % R
% Ser: 0 0 10 0 0 37 10 0 0 10 19 37 10 10 10 % S
% Thr: 0 0 0 0 0 10 0 28 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 10 0 0 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 73 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _